La sindrome delle unghie gialle

Translated title of the contribution: Yellow nail syndrome. Report of nine cases

A. Tosti, M. S. Guidetti, S. Lorenzi, C. Stinchi

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The yellow nail syndrome is a rare condition of unknown etiopathogenesis with chronic evolution characterized by three diagnostic signs: yellow nails, idiopathic lymphoedema and respiratory diseases. The distinctive nail changes that may appear several months or years before the other principal symptoms are the following: the nails cease or almost cease growing, they become excessively curved from side to side and their cuticle is usually absent. We report the therapeutic results obtained in 9 patients affected by the yellow nail syndrome who were treated with vit. E (600-1200 mg/daily) and/or itraconazole (400 mg/daily for one week a month). Our experience, even if limited, confirms the variable efficacy of vit. E (2 cured patients of the 8 patients treated) and the successful effects of itraconazole that probably depend on faster nail growth.

Translated title of the contributionYellow nail syndrome. Report of nine cases
Original languageItalian
Pages (from-to)255-258
Number of pages4
JournalGiornale Italiano di Dermatologia e Venereologia
Issue number4
StatePublished - 1997
Externally publishedYes


  • itraconazole, therapeutic use
  • nail diseases
  • vitamin E, therapeutic use

ASJC Scopus subject areas

  • Dermatology


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