X-ray monitoring of laser interstitial thermotherapy (LITT) in ex vivo porcine tissue

A. M. Minhaj, Fabrice Manns, P. J. Milne, D. B. Denham, Nelson Salas, Jean-Marie A Parel, D. S. Robinson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Experiments on the feasibility of X-ray monitoring of laser interstitial thermotherapy (LITT) of breast cancer are presented. Digital images of heated tissue phantoms (including fatty porcine tissue and polyacrylamide/acrylate hydrogel), obtained from an X-ray stereotactic biopsy system, were analyzed for changes in pixel intensity. Tissue phantoms were heated either by a 980 nm diode laser or by resistive heating elements in a custom-made chamber. Analysis was conducted by evaluating the changes in average pixel intensity of regions of interest. Image constancy and stability of the X-ray system were also investigated. Slight changes (<5%) dependent on the temperature of the tissue phantom were observed, while changes caused by heat-induced tissue displacement and/or shrinkage were more significant (>10%).

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsR.R. Anderson, K.E. Bartels, L.S. Bass, C.G. Garrett
Pages500-507
Number of pages8
Volume4244
DOIs
StatePublished - 2001
EventLaser in Surgery: Advanced Characterization, Therapeutics, and Systems XI - San Jose,CA, United States
Duration: Jun 20 2001Jun 23 2001

Other

OtherLaser in Surgery: Advanced Characterization, Therapeutics, and Systems XI
CountryUnited States
CitySan Jose,CA
Period6/20/016/23/01

Fingerprint

interstitials
Tissue
X rays
Lasers
Monitoring
Pixels
pixels
lasers
Electric heating elements
x rays
Biopsy
acrylates
Polyacrylates
Hydrogels
breast
Semiconductor lasers
chambers
cancer
semiconductor lasers
heating

Keywords

  • Breast cancer
  • Laser hyperthermia
  • LITT
  • Mammography
  • Monitoring
  • Temperature

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Minhaj, A. M., Manns, F., Milne, P. J., Denham, D. B., Salas, N., Parel, J-M. A., & Robinson, D. S. (2001). X-ray monitoring of laser interstitial thermotherapy (LITT) in ex vivo porcine tissue. In R. R. Anderson, K. E. Bartels, L. S. Bass, & C. G. Garrett (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4244, pp. 500-507) https://doi.org/10.1117/12.427841

X-ray monitoring of laser interstitial thermotherapy (LITT) in ex vivo porcine tissue. / Minhaj, A. M.; Manns, Fabrice; Milne, P. J.; Denham, D. B.; Salas, Nelson; Parel, Jean-Marie A; Robinson, D. S.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / R.R. Anderson; K.E. Bartels; L.S. Bass; C.G. Garrett. Vol. 4244 2001. p. 500-507.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Minhaj, AM, Manns, F, Milne, PJ, Denham, DB, Salas, N, Parel, J-MA & Robinson, DS 2001, X-ray monitoring of laser interstitial thermotherapy (LITT) in ex vivo porcine tissue. in RR Anderson, KE Bartels, LS Bass & CG Garrett (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4244, pp. 500-507, Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI, San Jose,CA, United States, 6/20/01. https://doi.org/10.1117/12.427841
Minhaj AM, Manns F, Milne PJ, Denham DB, Salas N, Parel J-MA et al. X-ray monitoring of laser interstitial thermotherapy (LITT) in ex vivo porcine tissue. In Anderson RR, Bartels KE, Bass LS, Garrett CG, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4244. 2001. p. 500-507 https://doi.org/10.1117/12.427841
Minhaj, A. M. ; Manns, Fabrice ; Milne, P. J. ; Denham, D. B. ; Salas, Nelson ; Parel, Jean-Marie A ; Robinson, D. S. / X-ray monitoring of laser interstitial thermotherapy (LITT) in ex vivo porcine tissue. Proceedings of SPIE - The International Society for Optical Engineering. editor / R.R. Anderson ; K.E. Bartels ; L.S. Bass ; C.G. Garrett. Vol. 4244 2001. pp. 500-507
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