Wounds and malignancy.

Jennifer T. Trent, Robert Kirsner

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Due to the prevalence of skin cancers, health care practitioners involved with wound management are likely to encounter cutaneous malignancies as part of their practice. This article focuses on 2 ways in which malignancies and wounds are related: the malignant degeneration of chronic wounds into cancer and malignancies that present as chronic wounds. The most common scenario in which chronic wounds have been associated with the development of squamous cell carcinoma is in the presence of chronic osteomyelitis. However, wounds secondary to burns, trauma, radiotherapy, and diabetes are also at risk for malignant degeneration. It is often difficult to distinguish malignant transformations from primary malignant ulcers. Given the uncommon nature of degeneration of a chronic wound or a malignancy presenting as a chronic wound, some suggest that only suspicious wounds undergo biopsy. Primary malignancy should be considered if the ulcer has a relatively short duration and the patient does not have a history of prior radiotherapy. Until recently, amputation has been the treatment of choice for squamous cell carcinomas that arose within chronic wounds associated with chronic osteomyelitis; however, other reports have shown that other methods of ensuring complete local excision are also useful.

Original languageEnglish
Pages (from-to)31-34
Number of pages4
JournalAdvances in skin & wound care
Volume16
Issue number1
StatePublished - Jan 1 2003

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Wounds and Injuries
Neoplasms
Osteomyelitis
Ulcer
Squamous Cell Carcinoma
Radiotherapy
Skin Neoplasms
Burns
Amputation
Delivery of Health Care
Biopsy
Skin

Cite this

Wounds and malignancy. / Trent, Jennifer T.; Kirsner, Robert.

In: Advances in skin & wound care, Vol. 16, No. 1, 01.01.2003, p. 31-34.

Research output: Contribution to journalArticle

Trent, JT & Kirsner, R 2003, 'Wounds and malignancy.', Advances in skin & wound care, vol. 16, no. 1, pp. 31-34.
Trent, Jennifer T. ; Kirsner, Robert. / Wounds and malignancy. In: Advances in skin & wound care. 2003 ; Vol. 16, No. 1. pp. 31-34.
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