Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans

Ruikang K. Wang, Anqi Zhang, W. O O June Choi, Qinqin Zhang, Chieh L I Chen, Andrew Miller, Giovanni Gregori, Philip J Rosenfeld

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the requirement of a repeated scanning protocol. This Letter evaluates the possibility of using only two repeated B-scans for OCTA for the purpose of an increased FOV. The effect of repeated numbers on the OCTA result is discussed through experiments on an animal model in vivo and evaluated using quantitative metrics for image quality. Demonstrated through in vivo imaging of a pathological human eye, we show that optical microangiography-based OCTA with two repeated B-scans can provide wide-field angiography up to 12 ? 12 mm with clinically acceptable image quality

Original languageEnglish (US)
Pages (from-to)2330-2333
Number of pages4
JournalOptics Letters
Volume41
Issue number10
DOIs
StatePublished - May 15 2016

Fingerprint

angiography
tomography
field of view
ophthalmology
animal models
requirements
scanning

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Wang, R. K., Zhang, A., June Choi, W. O. O., Zhang, Q., Chen, C. L. I., Miller, A., ... Rosenfeld, P. J. (2016). Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans. Optics Letters, 41(10), 2330-2333. https://doi.org/10.1364/OL.41.002330

Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans. / Wang, Ruikang K.; Zhang, Anqi; June Choi, W. O O; Zhang, Qinqin; Chen, Chieh L I; Miller, Andrew; Gregori, Giovanni; Rosenfeld, Philip J.

In: Optics Letters, Vol. 41, No. 10, 15.05.2016, p. 2330-2333.

Research output: Contribution to journalArticle

Wang RK, Zhang A, June Choi WOO, Zhang Q, Chen CLI, Miller A et al. Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans. Optics Letters. 2016 May 15;41(10):2330-2333. https://doi.org/10.1364/OL.41.002330
Wang, Ruikang K. ; Zhang, Anqi ; June Choi, W. O O ; Zhang, Qinqin ; Chen, Chieh L I ; Miller, Andrew ; Gregori, Giovanni ; Rosenfeld, Philip J. / Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans. In: Optics Letters. 2016 ; Vol. 41, No. 10. pp. 2330-2333.
@article{368c8a1aea55461ba9d95154310ece22,
title = "Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans",
abstract = "Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the requirement of a repeated scanning protocol. This Letter evaluates the possibility of using only two repeated B-scans for OCTA for the purpose of an increased FOV. The effect of repeated numbers on the OCTA result is discussed through experiments on an animal model in vivo and evaluated using quantitative metrics for image quality. Demonstrated through in vivo imaging of a pathological human eye, we show that optical microangiography-based OCTA with two repeated B-scans can provide wide-field angiography up to 12 ? 12 mm with clinically acceptable image quality",
author = "Wang, {Ruikang K.} and Anqi Zhang and {June Choi}, {W. O O} and Qinqin Zhang and Chen, {Chieh L I} and Andrew Miller and Giovanni Gregori and Rosenfeld, {Philip J}",
year = "2016",
month = "5",
day = "15",
doi = "10.1364/OL.41.002330",
language = "English (US)",
volume = "41",
pages = "2330--2333",
journal = "Optics Letters",
issn = "0146-9592",
publisher = "The Optical Society",
number = "10",

}

TY - JOUR

T1 - Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans

AU - Wang, Ruikang K.

AU - Zhang, Anqi

AU - June Choi, W. O O

AU - Zhang, Qinqin

AU - Chen, Chieh L I

AU - Miller, Andrew

AU - Gregori, Giovanni

AU - Rosenfeld, Philip J

PY - 2016/5/15

Y1 - 2016/5/15

N2 - Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the requirement of a repeated scanning protocol. This Letter evaluates the possibility of using only two repeated B-scans for OCTA for the purpose of an increased FOV. The effect of repeated numbers on the OCTA result is discussed through experiments on an animal model in vivo and evaluated using quantitative metrics for image quality. Demonstrated through in vivo imaging of a pathological human eye, we show that optical microangiography-based OCTA with two repeated B-scans can provide wide-field angiography up to 12 ? 12 mm with clinically acceptable image quality

AB - Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the requirement of a repeated scanning protocol. This Letter evaluates the possibility of using only two repeated B-scans for OCTA for the purpose of an increased FOV. The effect of repeated numbers on the OCTA result is discussed through experiments on an animal model in vivo and evaluated using quantitative metrics for image quality. Demonstrated through in vivo imaging of a pathological human eye, we show that optical microangiography-based OCTA with two repeated B-scans can provide wide-field angiography up to 12 ? 12 mm with clinically acceptable image quality

UR - http://www.scopus.com/inward/record.url?scp=84971325269&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84971325269&partnerID=8YFLogxK

U2 - 10.1364/OL.41.002330

DO - 10.1364/OL.41.002330

M3 - Article

AN - SCOPUS:84971325269

VL - 41

SP - 2330

EP - 2333

JO - Optics Letters

JF - Optics Letters

SN - 0146-9592

IS - 10

ER -