Whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography

Jianguang Zhong, Aizhu Tao, Zhe Xu, Hong Jiang, Yilei Shao, Huicheng Zhang, Che Liu, Jianhua Wang

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Abstract

Purpose To investigate changes of whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography (UL-OCT). Design Prospective, observational case series. Methods Twenty-one adult subjects were enrolled. Using UL-OCT, the left eye of each subject was imaged with relaxed diopters (0 D) and accommodative stimuli (+6 D). Full eye biometry included central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness, vitreous length, and axial length (AL). Results During accommodation (+6 D), the axial biometry of the whole eye changed significantly. Compared to the rest state, ACD at the accommodative state decreased significantly from 3.128 ± 0.305 mm to 2.961 ± 0.298 mm (paired t test, P <.001). The lens thickness increased significantly from 3.723 ± 0.237 mm to 3.963 ± 0.234 mm (P <.001). The vitreous length decreased significantly from 17.129 ± 0.864 mm to 17.057 ± 0.848 mm (P <.001). AL was 24.519 ± 0.917 mm at the rest state and increased to 24.545 ± 0.915 mm with +6 D accommodation stimulus. The elongated AL of 26.1 ± 13.4 μm between the rest and accommodative states was significant (P <.001). Conclusions During accommodation, whole eye axial biometry changed, including a decrease in ACD and vitreous length and an increase in lens thickness and AL. UL-OCT provides an alternative method that is suitable for full eye biometry during accommodation.

Original languageEnglish
JournalAmerican Journal of Ophthalmology
Volume157
Issue number5
DOIs
StatePublished - Jan 1 2014

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Biometry
Optical Coherence Tomography
Anterior Chamber
Lenses

ASJC Scopus subject areas

  • Ophthalmology

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Whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography. / Zhong, Jianguang; Tao, Aizhu; Xu, Zhe; Jiang, Hong; Shao, Yilei; Zhang, Huicheng; Liu, Che; Wang, Jianhua.

In: American Journal of Ophthalmology, Vol. 157, No. 5, 01.01.2014.

Research output: Contribution to journalArticle

Zhong, Jianguang ; Tao, Aizhu ; Xu, Zhe ; Jiang, Hong ; Shao, Yilei ; Zhang, Huicheng ; Liu, Che ; Wang, Jianhua. / Whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography. In: American Journal of Ophthalmology. 2014 ; Vol. 157, No. 5.
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