Where to Next for Optimizing Adherence in Large-Scale Trials of Continuous Positive Airway Pressure?

Amy M. Sawyer, Douglas M. Wallace, Luis F. Buenaver, Alexa J. Watach, Amy Blase, Bruno Saconi, Sanjay R. Patel, Samuel T. Kuna, Naresh M. Punjabi

Research output: Contribution to journalReview articlepeer-review

Abstract

Large-scale randomized trials of positive airway pressure (PAP) efficacy have been largely negative but PAP adherence was notably suboptimal across the trials. To address this limitation, evidence-based PAP adherence protocols embedded within the larger trial protocol are recommended. The complexity of such protocols depends on adequacy of resources, including funding and inclusion of behavioral scientist experts on the scientific team, and trial-specific considerations (eg, target population) and methods. Recommendations for optimizing PAP adherence in large-scale trials are set forth that address rigor and reproducibility.

Original languageEnglish (US)
Pages (from-to)125-144
Number of pages20
JournalSleep Medicine Clinics
Volume16
Issue number1
DOIs
StatePublished - Mar 2021
Externally publishedYes

Keywords

  • Behavioral economics
  • Continuous positive airway pressure
  • Controlled clinical trial
  • Health behavior
  • Health education
  • Obstructive sleep apnea
  • Patient compliance
  • Telemedicine

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health

Fingerprint

Dive into the research topics of 'Where to Next for Optimizing Adherence in Large-Scale Trials of Continuous Positive Airway Pressure?'. Together they form a unique fingerprint.

Cite this