When a human tumor xenograft is not a human tumor

A. Krishan

Research output: Contribution to journalEditorial

3 Scopus citations

Abstract

Human tumors grown as xenografts in athymic nude mice are important tools for the study of tumor biology and experimental therapy. However, data presented by Pathak et al. indicate that a significant number of the xenografts they examined were not of human origin. Utilization of methods to confirm the human origin of xenografts in athymic mice is highly recommended. Human tumor xenografts in athymic nude mice must be checked for authenticity because they may either be contaminated with mouse host cells or consist only of transformed mouse cells.

Original languageEnglish (US)
Pages (from-to)1889-1890
Number of pages2
JournalCancer
Volume83
Issue number9
DOIs
StatePublished - Nov 1 1998

    Fingerprint

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this