What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations

Orestis A. Panagiotou, John P.A. Ioannidis, Joel N. Hirschhorn, Goncalo R. Abecasis, Timothy M. Frayling, Mark I. McCarthy, Cecilia M. Lindgren, Terri H. Beaty, Nicholas Eriksson, Constantin Polychronakos, Sekar Kathirensan, Robert M. Plenge, Richard Spritz, Haydeh Payami, Eden R. Martin, Jeffery Vance, Wen Hui Su, Yu Sun Chang, Jin Xin Bei, Yi Xin ZengGuillaume Paré, Stephen V. Faraone, Benjamine Neale, Richard J. Anney, Bryan J. Traynor, André Scherag, Johannes Hebebrand, Anke Hinney, Philippe Froguel, David Meyre, Stephen J. Chanock, Wang Kesheng

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