Abstract
Despite more than a hundred years of professional hair research, and substantial recent progress in unravelling the molecular controls of hair follicle morphogenesis, the chronobiological control system that cyclically drives the hair follicle through dramatic remodelling processes between phases of growth (anagen), regression (catagen), and relative resting (telogen) have remained disappointingly obscure. In view of the vast literature that has become available over the past decades on numerous genetic, biochemical, cellular and pharmacological aspects of hair growth follicle control under physiological and pathological conditions, it is astounding how comparatively few researchers in the field have published theoretical concepts that explore how hair follicle cycling might be controlled. Since this question is at the very heart of basic and clinically applied hair biology, it deserves a much more systematic and serious public exploration, which the following contributions are designed to stimulate.
| Original language | English (US) |
|---|---|
| Journal | Experimental Dermatology |
| Volume | 8 |
| Issue number | 4 |
| State | Published - Aug 1 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Dermatology
Cite this
What controls hair follicle cycling? / Stenn, K. S.; Paus, Ralf.
In: Experimental Dermatology, Vol. 8, No. 4, 01.08.1999.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - What controls hair follicle cycling?
AU - Stenn, K. S.
AU - Paus, Ralf
PY - 1999/8/1
Y1 - 1999/8/1
N2 - Despite more than a hundred years of professional hair research, and substantial recent progress in unravelling the molecular controls of hair follicle morphogenesis, the chronobiological control system that cyclically drives the hair follicle through dramatic remodelling processes between phases of growth (anagen), regression (catagen), and relative resting (telogen) have remained disappointingly obscure. In view of the vast literature that has become available over the past decades on numerous genetic, biochemical, cellular and pharmacological aspects of hair growth follicle control under physiological and pathological conditions, it is astounding how comparatively few researchers in the field have published theoretical concepts that explore how hair follicle cycling might be controlled. Since this question is at the very heart of basic and clinically applied hair biology, it deserves a much more systematic and serious public exploration, which the following contributions are designed to stimulate.
AB - Despite more than a hundred years of professional hair research, and substantial recent progress in unravelling the molecular controls of hair follicle morphogenesis, the chronobiological control system that cyclically drives the hair follicle through dramatic remodelling processes between phases of growth (anagen), regression (catagen), and relative resting (telogen) have remained disappointingly obscure. In view of the vast literature that has become available over the past decades on numerous genetic, biochemical, cellular and pharmacological aspects of hair growth follicle control under physiological and pathological conditions, it is astounding how comparatively few researchers in the field have published theoretical concepts that explore how hair follicle cycling might be controlled. Since this question is at the very heart of basic and clinically applied hair biology, it deserves a much more systematic and serious public exploration, which the following contributions are designed to stimulate.
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UR - http://www.scopus.com/inward/citedby.url?scp=0033174886&partnerID=8YFLogxK
M3 - Review article
VL - 8
JO - Experimental Dermatology
JF - Experimental Dermatology
SN - 0906-6705
IS - 4
ER -