Wernicke's encephalopathy in AIDS: A preventable cause of fatal neurological deficit

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19 Citations (Scopus)

Abstract

Wernicke's encephalopathy is commonly associated with chronic alcohol abuse, but may also occur in patients with poor nutritional status. We report a case of acute Wernicke's encephalopathy in a patient with AIDS without any predisposing risk factors for thiamine deficiency. In developing countries, without vitamin supplementation, this disorder may play a role in the morbidity and mortality associated with AIDS. We believe that thiamine supplementation should be considered in cachetic AIDS patients, especially where access to antiretroviral therapy is limited.

Original languageEnglish
Pages (from-to)712-713
Number of pages2
JournalInternational Journal of STD and AIDS
Volume14
Issue number10
DOIs
StatePublished - Oct 1 2003

Fingerprint

Wernicke Encephalopathy
Acquired Immunodeficiency Syndrome
Thiamine Deficiency
Thiamine
Nutritional Status
Vitamins
Causality
Developing Countries
Alcoholism
Morbidity
Mortality
Therapeutics

Keywords

  • AIDS
  • Cachexia
  • Thiamine deficiency
  • Wernicke's encephalopathy

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Immunology

Cite this

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abstract = "Wernicke's encephalopathy is commonly associated with chronic alcohol abuse, but may also occur in patients with poor nutritional status. We report a case of acute Wernicke's encephalopathy in a patient with AIDS without any predisposing risk factors for thiamine deficiency. In developing countries, without vitamin supplementation, this disorder may play a role in the morbidity and mortality associated with AIDS. We believe that thiamine supplementation should be considered in cachetic AIDS patients, especially where access to antiretroviral therapy is limited.",
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T1 - Wernicke's encephalopathy in AIDS

T2 - A preventable cause of fatal neurological deficit

AU - Alcaide, Maria L

AU - Jayaweera, Dushyantha T

AU - Espinoza, Luis

AU - Kolber, Michael A

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N2 - Wernicke's encephalopathy is commonly associated with chronic alcohol abuse, but may also occur in patients with poor nutritional status. We report a case of acute Wernicke's encephalopathy in a patient with AIDS without any predisposing risk factors for thiamine deficiency. In developing countries, without vitamin supplementation, this disorder may play a role in the morbidity and mortality associated with AIDS. We believe that thiamine supplementation should be considered in cachetic AIDS patients, especially where access to antiretroviral therapy is limited.

AB - Wernicke's encephalopathy is commonly associated with chronic alcohol abuse, but may also occur in patients with poor nutritional status. We report a case of acute Wernicke's encephalopathy in a patient with AIDS without any predisposing risk factors for thiamine deficiency. In developing countries, without vitamin supplementation, this disorder may play a role in the morbidity and mortality associated with AIDS. We believe that thiamine supplementation should be considered in cachetic AIDS patients, especially where access to antiretroviral therapy is limited.

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KW - Cachexia

KW - Thiamine deficiency

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