Weighted criteria for the diagnosis of systemic lupus erythematosus

J. D. Clough, M. Elrazak, L. H. Calabrese, R. Valenzuela, W. B. Braun, G. W. Williams

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The preliminary American Rheumatism Association (ARA) criteria for classification of systemic lupus erythematosus (SLE) were evaluated for sensitivity and specificity in 87 patients with SLE and 73 without SLE from a rheumatology population. Using these data, Bayes' theorem was employed to weight the criteria so that a scoring system could be developed, allowing more accurate use of the criteria in diagnosis. Combinations of serologic test results were evaluated in a similar manner. Comparison of weighted scores with criteria counts showed greater sensitivity and specificity of the former whether the 1971 or modified 1982 ARA criteria were used. Weighted criteria may be more useful in clearly defining patient populations for studies of SLE.

Original languageEnglish
Pages (from-to)281-285
Number of pages5
JournalArchives of Internal Medicine
Volume144
Issue number2
DOIs
StatePublished - Apr 5 1984
Externally publishedYes

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Systemic Lupus Erythematosus
Rheumatic Diseases
Sensitivity and Specificity
Bayes Theorem
Rheumatology
Serologic Tests
Population
Weights and Measures

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Clough, J. D., Elrazak, M., Calabrese, L. H., Valenzuela, R., Braun, W. B., & Williams, G. W. (1984). Weighted criteria for the diagnosis of systemic lupus erythematosus. Archives of Internal Medicine, 144(2), 281-285. https://doi.org/10.1001/archinte.144.2.281

Weighted criteria for the diagnosis of systemic lupus erythematosus. / Clough, J. D.; Elrazak, M.; Calabrese, L. H.; Valenzuela, R.; Braun, W. B.; Williams, G. W.

In: Archives of Internal Medicine, Vol. 144, No. 2, 05.04.1984, p. 281-285.

Research output: Contribution to journalArticle

Clough, JD, Elrazak, M, Calabrese, LH, Valenzuela, R, Braun, WB & Williams, GW 1984, 'Weighted criteria for the diagnosis of systemic lupus erythematosus', Archives of Internal Medicine, vol. 144, no. 2, pp. 281-285. https://doi.org/10.1001/archinte.144.2.281
Clough JD, Elrazak M, Calabrese LH, Valenzuela R, Braun WB, Williams GW. Weighted criteria for the diagnosis of systemic lupus erythematosus. Archives of Internal Medicine. 1984 Apr 5;144(2):281-285. https://doi.org/10.1001/archinte.144.2.281
Clough, J. D. ; Elrazak, M. ; Calabrese, L. H. ; Valenzuela, R. ; Braun, W. B. ; Williams, G. W. / Weighted criteria for the diagnosis of systemic lupus erythematosus. In: Archives of Internal Medicine. 1984 ; Vol. 144, No. 2. pp. 281-285.
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