We Could Use More Tolerance: Role of Intestinal-Allograft-Derived Human Stem Cells

Norma Sue Kenyon

doi:10.1016/j.stem.2019.01.009

We Could Use More Tolerance: Role of Intestinal-Allograft-Derived Human Stem Cells

Norma Sue Kenyon

Surgery

Research output: Contribution to journal › Short survey › peer-review

Abstract

Mixed chimerism is associated with allograft acceptance and tolerance. In this issue of Cell Stem Cell, Fu et al. (2019) provide evidence that functional, donor-derived hematopoietic stem and progenitor cells in the intestinal allograft can persist long-term, contribute to multi-lineage chimerism in the circulation, and result in T cell tolerance through host lymphoid organ selection.

Original language	English (US)
Pages (from-to)	197-198
Number of pages	2
Journal	Cell Stem Cell
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/j.stem.2019.01.009
State	Published - Feb 7 2019

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2019.01.009

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abstract = "Mixed chimerism is associated with allograft acceptance and tolerance. In this issue of Cell Stem Cell, Fu et al. (2019) provide evidence that functional, donor-derived hematopoietic stem and progenitor cells in the intestinal allograft can persist long-term, contribute to multi-lineage chimerism in the circulation, and result in T cell tolerance through host lymphoid organ selection.",

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