Voriconazole and fungal keratitis: A report of two treatment failures

JoAnn A. Giaconi, Fabiana B. Marangon, Darlene Miller, Eduardo C Alfonso

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Two cases of fungal keratitis, one caused by Fusarium oxysporum and the other by Colletotrichum dematium, that failed treatment with topical voriconazole 1% are presented. These cases are noteworthy in that topical voriconazole was unable to eradicate the corneal infection in both cases, despite relatively low MIC90 tested for each species of 8 and 1 μg/mL, respectively.

Original languageEnglish
Pages (from-to)437-439
Number of pages3
JournalJournal of Ocular Pharmacology and Therapeutics
Volume22
Issue number6
DOIs
StatePublished - Dec 1 2006

Fingerprint

Keratitis
Treatment Failure
Colletotrichum
Fusarium
Infection
Voriconazole

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Ophthalmology
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Voriconazole and fungal keratitis : A report of two treatment failures. / Giaconi, JoAnn A.; Marangon, Fabiana B.; Miller, Darlene; Alfonso, Eduardo C.

In: Journal of Ocular Pharmacology and Therapeutics, Vol. 22, No. 6, 01.12.2006, p. 437-439.

Research output: Contribution to journalArticle

@article{c9c5a59a1d1d4c1581b40b44191f17dd,
title = "Voriconazole and fungal keratitis: A report of two treatment failures",
abstract = "Two cases of fungal keratitis, one caused by Fusarium oxysporum and the other by Colletotrichum dematium, that failed treatment with topical voriconazole 1{\%} are presented. These cases are noteworthy in that topical voriconazole was unable to eradicate the corneal infection in both cases, despite relatively low MIC90 tested for each species of 8 and 1 μg/mL, respectively.",
author = "Giaconi, {JoAnn A.} and Marangon, {Fabiana B.} and Darlene Miller and Alfonso, {Eduardo C}",
year = "2006",
month = "12",
day = "1",
doi = "10.1089/jop.2006.22.437",
language = "English",
volume = "22",
pages = "437--439",
journal = "Journal of Ocular Pharmacology and Therapeutics",
issn = "1080-7683",
publisher = "Mary Ann Liebert Inc.",
number = "6",

}

TY - JOUR

T1 - Voriconazole and fungal keratitis

T2 - A report of two treatment failures

AU - Giaconi, JoAnn A.

AU - Marangon, Fabiana B.

AU - Miller, Darlene

AU - Alfonso, Eduardo C

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Two cases of fungal keratitis, one caused by Fusarium oxysporum and the other by Colletotrichum dematium, that failed treatment with topical voriconazole 1% are presented. These cases are noteworthy in that topical voriconazole was unable to eradicate the corneal infection in both cases, despite relatively low MIC90 tested for each species of 8 and 1 μg/mL, respectively.

AB - Two cases of fungal keratitis, one caused by Fusarium oxysporum and the other by Colletotrichum dematium, that failed treatment with topical voriconazole 1% are presented. These cases are noteworthy in that topical voriconazole was unable to eradicate the corneal infection in both cases, despite relatively low MIC90 tested for each species of 8 and 1 μg/mL, respectively.

UR - http://www.scopus.com/inward/record.url?scp=33846227148&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846227148&partnerID=8YFLogxK

U2 - 10.1089/jop.2006.22.437

DO - 10.1089/jop.2006.22.437

M3 - Article

C2 - 17238810

AN - SCOPUS:33846227148

VL - 22

SP - 437

EP - 439

JO - Journal of Ocular Pharmacology and Therapeutics

JF - Journal of Ocular Pharmacology and Therapeutics

SN - 1080-7683

IS - 6

ER -