Von Willebrand factor antigen levels in Kaposi's sarcoma

N. S. Penneys, R. Kott-Blumenkranz, Francisco Civantos, J. Kent

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Consistent elevations of plasma von Willebrand factor antigen were observed in otherwise healthy elderly patients with Kaposi's sarcoma. The elevations were predominantly of the endothelial cell-derived antigen, as opposed to the factor VIII procoagulant, with resultant elevations in the antigen/procoagulant ratios. Lesser elevations were seen in a group of age-matched control subjects who did not have Kaposi's sarcoma or intercurrent illness. The greater elevations in plasma von Willebrand factor antigen therefore appear to be the direct consequence of the presence of Kaposi's sarcoma cells. Our findings also suggest that there is a direct relationship between tumor load and degree of von Willebrand factor antigen elevation.

Original languageEnglish
Pages (from-to)1214-1217
Number of pages4
JournalJournal of the American Academy of Dermatology
Volume15
Issue number6
StatePublished - Dec 1 1986

Fingerprint

Kaposi's Sarcoma
von Willebrand Factor
Antigens
Factor VIII
Tumor Burden
Research Design
Endothelial Cells
Age Groups
Von Willebrand antigen

ASJC Scopus subject areas

  • Dermatology

Cite this

Penneys, N. S., Kott-Blumenkranz, R., Civantos, F., & Kent, J. (1986). Von Willebrand factor antigen levels in Kaposi's sarcoma. Journal of the American Academy of Dermatology, 15(6), 1214-1217.

Von Willebrand factor antigen levels in Kaposi's sarcoma. / Penneys, N. S.; Kott-Blumenkranz, R.; Civantos, Francisco; Kent, J.

In: Journal of the American Academy of Dermatology, Vol. 15, No. 6, 01.12.1986, p. 1214-1217.

Research output: Contribution to journalArticle

Penneys, NS, Kott-Blumenkranz, R, Civantos, F & Kent, J 1986, 'Von Willebrand factor antigen levels in Kaposi's sarcoma', Journal of the American Academy of Dermatology, vol. 15, no. 6, pp. 1214-1217.
Penneys, N. S. ; Kott-Blumenkranz, R. ; Civantos, Francisco ; Kent, J. / Von Willebrand factor antigen levels in Kaposi's sarcoma. In: Journal of the American Academy of Dermatology. 1986 ; Vol. 15, No. 6. pp. 1214-1217.
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