Volume Guarantee Ventilation: Effect on Preterm Infants with Frequent Hypoxemia Episodes

Deepak Jain, Nelson R Claure, Carmen D'Ugard, Jose Bello, Eduardo Bancalari

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Preterm infants on mechanical ventilation have spontaneous hypoxemia episodes (HE) triggered by decreases in lung volume and tidal volume (VT). Volume guarantee (VG) is a mode where the ventilator peak pressure is adjusted to keep the exhaled VT at a target level. The effect of VG on HE under routine clinical conditions has not been fully evaluated. Objective: To evaluate the effect of VG on HE in preterm infants in comparison to pressure control (PC) ventilation under routine clinical conditions. Methods: Twenty-four mechanically ventilated preterm infants with ≥4 HE of arterial oxygen saturation (SpO2) 2 2 2 2) was lower during VG compared to PC. Conclusion: The use of VG during routine clinical conditions resulted in a modest reduction in the duration of HE (SpO2 2 compared to PC. The use of VG did not reduce the more severe HE.

Original languageEnglish (US)
Pages (from-to)129-134
Number of pages6
JournalNeonatology
DOIs
StateAccepted/In press - Apr 19 2016

Fingerprint

Premature Infants
Ventilation
Pressure
Tidal Volume
Mechanical Ventilators
Artificial Respiration
Hypoxia
Oxygen
Lung

Keywords

  • Arterial oxygen saturation#
  • Intermittent hypoxemia
  • Premature infant
  • Volume-targeted ventilation

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Cite this

Volume Guarantee Ventilation : Effect on Preterm Infants with Frequent Hypoxemia Episodes. / Jain, Deepak; Claure, Nelson R; D'Ugard, Carmen; Bello, Jose; Bancalari, Eduardo.

In: Neonatology, 19.04.2016, p. 129-134.

Research output: Contribution to journalArticle

@article{3b59b281fb14441f970090805f1abdd7,
title = "Volume Guarantee Ventilation: Effect on Preterm Infants with Frequent Hypoxemia Episodes",
abstract = "Background: Preterm infants on mechanical ventilation have spontaneous hypoxemia episodes (HE) triggered by decreases in lung volume and tidal volume (VT). Volume guarantee (VG) is a mode where the ventilator peak pressure is adjusted to keep the exhaled VT at a target level. The effect of VG on HE under routine clinical conditions has not been fully evaluated. Objective: To evaluate the effect of VG on HE in preterm infants in comparison to pressure control (PC) ventilation under routine clinical conditions. Methods: Twenty-four mechanically ventilated preterm infants with ≥4 HE of arterial oxygen saturation (SpO2) 2 2 2 2) was lower during VG compared to PC. Conclusion: The use of VG during routine clinical conditions resulted in a modest reduction in the duration of HE (SpO2 2 compared to PC. The use of VG did not reduce the more severe HE.",
keywords = "Arterial oxygen saturation#, Intermittent hypoxemia, Premature infant, Volume-targeted ventilation",
author = "Deepak Jain and Claure, {Nelson R} and Carmen D'Ugard and Jose Bello and Eduardo Bancalari",
year = "2016",
month = "4",
day = "19",
doi = "10.1159/000444844",
language = "English (US)",
pages = "129--134",
journal = "Neonatology",
issn = "1661-7800",
publisher = "S. Karger AG",

}

TY - JOUR

T1 - Volume Guarantee Ventilation

T2 - Effect on Preterm Infants with Frequent Hypoxemia Episodes

AU - Jain, Deepak

AU - Claure, Nelson R

AU - D'Ugard, Carmen

AU - Bello, Jose

AU - Bancalari, Eduardo

PY - 2016/4/19

Y1 - 2016/4/19

N2 - Background: Preterm infants on mechanical ventilation have spontaneous hypoxemia episodes (HE) triggered by decreases in lung volume and tidal volume (VT). Volume guarantee (VG) is a mode where the ventilator peak pressure is adjusted to keep the exhaled VT at a target level. The effect of VG on HE under routine clinical conditions has not been fully evaluated. Objective: To evaluate the effect of VG on HE in preterm infants in comparison to pressure control (PC) ventilation under routine clinical conditions. Methods: Twenty-four mechanically ventilated preterm infants with ≥4 HE of arterial oxygen saturation (SpO2) 2 2 2 2) was lower during VG compared to PC. Conclusion: The use of VG during routine clinical conditions resulted in a modest reduction in the duration of HE (SpO2 2 compared to PC. The use of VG did not reduce the more severe HE.

AB - Background: Preterm infants on mechanical ventilation have spontaneous hypoxemia episodes (HE) triggered by decreases in lung volume and tidal volume (VT). Volume guarantee (VG) is a mode where the ventilator peak pressure is adjusted to keep the exhaled VT at a target level. The effect of VG on HE under routine clinical conditions has not been fully evaluated. Objective: To evaluate the effect of VG on HE in preterm infants in comparison to pressure control (PC) ventilation under routine clinical conditions. Methods: Twenty-four mechanically ventilated preterm infants with ≥4 HE of arterial oxygen saturation (SpO2) 2 2 2 2) was lower during VG compared to PC. Conclusion: The use of VG during routine clinical conditions resulted in a modest reduction in the duration of HE (SpO2 2 compared to PC. The use of VG did not reduce the more severe HE.

KW - Arterial oxygen saturation#

KW - Intermittent hypoxemia

KW - Premature infant

KW - Volume-targeted ventilation

UR - http://www.scopus.com/inward/record.url?scp=84964241060&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964241060&partnerID=8YFLogxK

U2 - 10.1159/000444844

DO - 10.1159/000444844

M3 - Article

C2 - 27088487

AN - SCOPUS:84964241060

SP - 129

EP - 134

JO - Neonatology

JF - Neonatology

SN - 1661-7800

ER -