Abstract
Background: Preterm infants on mechanical ventilation have spontaneous hypoxemia episodes (HE) triggered by decreases in lung volume and tidal volume (VT). Volume guarantee (VG) is a mode where the ventilator peak pressure is adjusted to keep the exhaled VT at a target level. The effect of VG on HE under routine clinical conditions has not been fully evaluated. Objective: To evaluate the effect of VG on HE in preterm infants in comparison to pressure control (PC) ventilation under routine clinical conditions. Methods: Twenty-four mechanically ventilated preterm infants with ≥4 HE of arterial oxygen saturation (SpO2) 2 2 2 2) was lower during VG compared to PC. Conclusion: The use of VG during routine clinical conditions resulted in a modest reduction in the duration of HE (SpO2 2 compared to PC. The use of VG did not reduce the more severe HE.
Original language | English (US) |
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Pages (from-to) | 129-134 |
Number of pages | 6 |
Journal | Neonatology |
DOIs | |
State | Accepted/In press - Apr 19 2016 |
Keywords
- Arterial oxygen saturation#
- Intermittent hypoxemia
- Premature infant
- Volume-targeted ventilation
ASJC Scopus subject areas
- Developmental Biology
- Pediatrics, Perinatology, and Child Health