Abstract
Background: Preterm infants on mechanical ventilation have spontaneous hypoxemia episodes (HE) triggered by decreases in lung volume and tidal volume (VT). Volume guarantee (VG) is a mode where the ventilator peak pressure is adjusted to keep the exhaled VT at a target level. The effect of VG on HE under routine clinical conditions has not been fully evaluated. Objective: To evaluate the effect of VG on HE in preterm infants in comparison to pressure control (PC) ventilation under routine clinical conditions. Methods: Twenty-four mechanically ventilated preterm infants with ≥4 HE of arterial oxygen saturation (SpO2) 2 2 2 2) was lower during VG compared to PC. Conclusion: The use of VG during routine clinical conditions resulted in a modest reduction in the duration of HE (SpO2 2 compared to PC. The use of VG did not reduce the more severe HE.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 129-134 |
| Number of pages | 6 |
| Journal | Neonatology |
| DOIs | |
| State | Accepted/In press - Apr 19 2016 |
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Keywords
- Arterial oxygen saturation#
- Intermittent hypoxemia
- Premature infant
- Volume-targeted ventilation
ASJC Scopus subject areas
- Developmental Biology
- Pediatrics, Perinatology, and Child Health
Cite this
Volume Guarantee Ventilation : Effect on Preterm Infants with Frequent Hypoxemia Episodes. / Jain, Deepak; Claure, Nelson R; D'Ugard, Carmen; Bello, Jose; Bancalari, Eduardo.
In: Neonatology, 19.04.2016, p. 129-134.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Volume Guarantee Ventilation
T2 - Effect on Preterm Infants with Frequent Hypoxemia Episodes
AU - Jain, Deepak
AU - Claure, Nelson R
AU - D'Ugard, Carmen
AU - Bello, Jose
AU - Bancalari, Eduardo
PY - 2016/4/19
Y1 - 2016/4/19
N2 - Background: Preterm infants on mechanical ventilation have spontaneous hypoxemia episodes (HE) triggered by decreases in lung volume and tidal volume (VT). Volume guarantee (VG) is a mode where the ventilator peak pressure is adjusted to keep the exhaled VT at a target level. The effect of VG on HE under routine clinical conditions has not been fully evaluated. Objective: To evaluate the effect of VG on HE in preterm infants in comparison to pressure control (PC) ventilation under routine clinical conditions. Methods: Twenty-four mechanically ventilated preterm infants with ≥4 HE of arterial oxygen saturation (SpO2) 2 2 2 2) was lower during VG compared to PC. Conclusion: The use of VG during routine clinical conditions resulted in a modest reduction in the duration of HE (SpO2 2 compared to PC. The use of VG did not reduce the more severe HE.
AB - Background: Preterm infants on mechanical ventilation have spontaneous hypoxemia episodes (HE) triggered by decreases in lung volume and tidal volume (VT). Volume guarantee (VG) is a mode where the ventilator peak pressure is adjusted to keep the exhaled VT at a target level. The effect of VG on HE under routine clinical conditions has not been fully evaluated. Objective: To evaluate the effect of VG on HE in preterm infants in comparison to pressure control (PC) ventilation under routine clinical conditions. Methods: Twenty-four mechanically ventilated preterm infants with ≥4 HE of arterial oxygen saturation (SpO2) 2 2 2 2) was lower during VG compared to PC. Conclusion: The use of VG during routine clinical conditions resulted in a modest reduction in the duration of HE (SpO2 2 compared to PC. The use of VG did not reduce the more severe HE.
KW - Arterial oxygen saturation#
KW - Intermittent hypoxemia
KW - Premature infant
KW - Volume-targeted ventilation
UR - http://www.scopus.com/inward/record.url?scp=84964241060&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964241060&partnerID=8YFLogxK
U2 - 10.1159/000444844
DO - 10.1159/000444844
M3 - Article
C2 - 27088487
AN - SCOPUS:84964241060
SP - 129
EP - 134
JO - Neonatology
JF - Neonatology
SN - 1661-7800
ER -