Vocal fold augmentation with calcium hydroxylapatite (CaHA)

Clark A. Rosen, Jackie Gartner-Schmidt, Roy R Casiano, Timothy D. Anderson, Felicia Johnson, Lee Reussner, Marc Remacle, Robert T. Sataloff, Jean Abitbol, Gary Shaw, Sanford Archer, Andrew McWhorter

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Objectives: Evaluate the effectiveness of CaHA injection for patients with glottal incompetence. Methods: Multi-center, open-label, prospective clinical study with each patient serving as his/her own control. Voice-related outcome measures were collected for pre-injection and 1, 3, and 6 months. Results: Sixty-eight patients were available for evaluation. Fifty percent of the injection procedures were done in office. Fifty-seven percent were diagnosed with unilateral paralysis and 42% with glottal incompetence with mobile vocal folds. Patient satisfaction 6 months post showed 56% had significantly improved voice and 38% reported moderately improved voice. Paired t tests from baseline to 6 months showed significant improvements on the VHI and VAS (vocal effort), CAPE-V judgments of voice severity and videoendostroboscopy ratings of glottal closure, and objective voice measures of glottal closure (MPT and S:Z ratio). Conclusions: Preliminary results in this large cohort of patients demonstrate excellent clinical results.

Original languageEnglish
JournalOtolaryngology - Head and Neck Surgery
Volume136
Issue number2
DOIs
StatePublished - Feb 1 2007

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Vocal Cords
Durapatite
Calcium
Injections
Patient Satisfaction
Paralysis
Outcome Assessment (Health Care)
Prospective Studies

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Rosen, C. A., Gartner-Schmidt, J., Casiano, R. R., Anderson, T. D., Johnson, F., Reussner, L., ... McWhorter, A. (2007). Vocal fold augmentation with calcium hydroxylapatite (CaHA). Otolaryngology - Head and Neck Surgery, 136(2). https://doi.org/10.1016/j.otohns.2006.07.014

Vocal fold augmentation with calcium hydroxylapatite (CaHA). / Rosen, Clark A.; Gartner-Schmidt, Jackie; Casiano, Roy R; Anderson, Timothy D.; Johnson, Felicia; Reussner, Lee; Remacle, Marc; Sataloff, Robert T.; Abitbol, Jean; Shaw, Gary; Archer, Sanford; McWhorter, Andrew.

In: Otolaryngology - Head and Neck Surgery, Vol. 136, No. 2, 01.02.2007.

Research output: Contribution to journalArticle

Rosen, CA, Gartner-Schmidt, J, Casiano, RR, Anderson, TD, Johnson, F, Reussner, L, Remacle, M, Sataloff, RT, Abitbol, J, Shaw, G, Archer, S & McWhorter, A 2007, 'Vocal fold augmentation with calcium hydroxylapatite (CaHA)', Otolaryngology - Head and Neck Surgery, vol. 136, no. 2. https://doi.org/10.1016/j.otohns.2006.07.014
Rosen, Clark A. ; Gartner-Schmidt, Jackie ; Casiano, Roy R ; Anderson, Timothy D. ; Johnson, Felicia ; Reussner, Lee ; Remacle, Marc ; Sataloff, Robert T. ; Abitbol, Jean ; Shaw, Gary ; Archer, Sanford ; McWhorter, Andrew. / Vocal fold augmentation with calcium hydroxylapatite (CaHA). In: Otolaryngology - Head and Neck Surgery. 2007 ; Vol. 136, No. 2.
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AU - Reussner, Lee

AU - Remacle, Marc

AU - Sataloff, Robert T.

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