Vitreoretinal lymphoma followed by systemic diffuse large B cell lymphoma

Kenneth C. Fan, Kimberly D. Tran, J. William Harbour, Sander A. Dubovy, Nimesh A. Patel, Thomas A. Albini

Research output: Contribution to journalLetter

Abstract

Vitreoretinal lymphoma as the presenting diagnosis in association with a systemic lymphoma without central nervous system involvement is exceedingly rare, and the classification of this condition is not well-established. Here, we describe a patient with intermittent blurry vision in the left eye for 2 years in the setting of a recent incidental diagnosis of diffuse large B cell lymphoma from an axillary lymph node biopsy. The diagnosis of panuveitis with an extensive exudative retinal detachment was made. The patient was treated with pars plana vitrectomy as well as systemic chemotherapy, intrathecal methotrexate, intravitreal methotrexate, and intravitreal rituximab with good post-operative outcomes.

Original languageEnglish (US)
Article number11
JournalJournal of Ophthalmic Inflammation and Infection
Volume9
Issue number1
DOIs
StatePublished - Dec 1 2019

Fingerprint

Lymphoma, Large B-Cell, Diffuse
Lymphoma
Methotrexate
Panuveitis
Temazepam
Vitrectomy
Retinal Detachment
Central Nervous System
Lymph Nodes
Biopsy
Drug Therapy

ASJC Scopus subject areas

  • Ophthalmology
  • Infectious Diseases

Cite this

Vitreoretinal lymphoma followed by systemic diffuse large B cell lymphoma. / Fan, Kenneth C.; Tran, Kimberly D.; Harbour, J. William; Dubovy, Sander A.; Patel, Nimesh A.; Albini, Thomas A.

In: Journal of Ophthalmic Inflammation and Infection, Vol. 9, No. 1, 11, 01.12.2019.

Research output: Contribution to journalLetter

@article{ad198e7860494258a9907a25dce17cce,
title = "Vitreoretinal lymphoma followed by systemic diffuse large B cell lymphoma",
abstract = "Vitreoretinal lymphoma as the presenting diagnosis in association with a systemic lymphoma without central nervous system involvement is exceedingly rare, and the classification of this condition is not well-established. Here, we describe a patient with intermittent blurry vision in the left eye for 2 years in the setting of a recent incidental diagnosis of diffuse large B cell lymphoma from an axillary lymph node biopsy. The diagnosis of panuveitis with an extensive exudative retinal detachment was made. The patient was treated with pars plana vitrectomy as well as systemic chemotherapy, intrathecal methotrexate, intravitreal methotrexate, and intravitreal rituximab with good post-operative outcomes.",
author = "Fan, {Kenneth C.} and Tran, {Kimberly D.} and Harbour, {J. William} and Dubovy, {Sander A.} and Patel, {Nimesh A.} and Albini, {Thomas A.}",
year = "2019",
month = "12",
day = "1",
doi = "10.1186/s12348-019-0177-8",
language = "English (US)",
volume = "9",
journal = "Journal of Ophthalmic Inflammation and Infection",
issn = "1869-5760",
publisher = "Springer Verlag",
number = "1",

}

TY - JOUR

T1 - Vitreoretinal lymphoma followed by systemic diffuse large B cell lymphoma

AU - Fan, Kenneth C.

AU - Tran, Kimberly D.

AU - Harbour, J. William

AU - Dubovy, Sander A.

AU - Patel, Nimesh A.

AU - Albini, Thomas A.

PY - 2019/12/1

Y1 - 2019/12/1

N2 - Vitreoretinal lymphoma as the presenting diagnosis in association with a systemic lymphoma without central nervous system involvement is exceedingly rare, and the classification of this condition is not well-established. Here, we describe a patient with intermittent blurry vision in the left eye for 2 years in the setting of a recent incidental diagnosis of diffuse large B cell lymphoma from an axillary lymph node biopsy. The diagnosis of panuveitis with an extensive exudative retinal detachment was made. The patient was treated with pars plana vitrectomy as well as systemic chemotherapy, intrathecal methotrexate, intravitreal methotrexate, and intravitreal rituximab with good post-operative outcomes.

AB - Vitreoretinal lymphoma as the presenting diagnosis in association with a systemic lymphoma without central nervous system involvement is exceedingly rare, and the classification of this condition is not well-established. Here, we describe a patient with intermittent blurry vision in the left eye for 2 years in the setting of a recent incidental diagnosis of diffuse large B cell lymphoma from an axillary lymph node biopsy. The diagnosis of panuveitis with an extensive exudative retinal detachment was made. The patient was treated with pars plana vitrectomy as well as systemic chemotherapy, intrathecal methotrexate, intravitreal methotrexate, and intravitreal rituximab with good post-operative outcomes.

UR - http://www.scopus.com/inward/record.url?scp=85067015363&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85067015363&partnerID=8YFLogxK

U2 - 10.1186/s12348-019-0177-8

DO - 10.1186/s12348-019-0177-8

M3 - Letter

AN - SCOPUS:85067015363

VL - 9

JO - Journal of Ophthalmic Inflammation and Infection

JF - Journal of Ophthalmic Inflammation and Infection

SN - 1869-5760

IS - 1

M1 - 11

ER -