Visuospatial working memory in schizotypal personality disorder patients

Sonia E. Lees Roitman, Vivian Mitropoulou, Richard S E Keefe, Jeremy M. Silverman, Michael Serby, Philip D Harvey, Diedre A. Reynolds, Richard C. Mohs, Larry J. Siever

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Background: Cognitive processing deficits have been identified as an abnormality that schizotypal personality disorder (SPD) individuals share with schizophrenic patients. It has been hypothesized that impaired working memory may be a critical component of several of the more complex cognitive deficits found in schizophrenia spectrum patients. Method: 18 DSM-III-R SPD patients, and 17 normal comparison subjects were compared on a pen and paper visuospatial working memory task. Moreover, we identified a second psychiatric comparison group comprised of nine patients with other, non-odd cluster personality disorder diagnoses who met no more than one of the SPD criteria and were also tested on the same task. Each person was given 14 immediate recall trials and 10 trials using a 10 s delay. Results: SPD patients performed significantly worse than normal control subjects on the working memory task. SPD patients also performed significantly worse compared to the non-schizophrenia-related personality disorder psychiatric comparison group. Conclusions: Like schizophrenic patients, SPD patients demonstrate working memory impairment compared to normal controls. This impairment may be specific to the schizophrenia-related personality disorders. (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)447-455
Number of pages9
JournalSchizophrenia Research
Volume41
Issue number3
DOIs
StatePublished - Feb 14 2000
Externally publishedYes

Fingerprint

Schizotypal Personality Disorder
Short-Term Memory
Personality Disorders
Psychiatry
Schizophrenia
Diagnostic and Statistical Manual of Mental Disorders

Keywords

  • Cognitive deficits
  • Personality disorders
  • Schizophrenia
  • Visuospatial memory

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

Cite this

Lees Roitman, S. E., Mitropoulou, V., Keefe, R. S. E., Silverman, J. M., Serby, M., Harvey, P. D., ... Siever, L. J. (2000). Visuospatial working memory in schizotypal personality disorder patients. Schizophrenia Research, 41(3), 447-455. https://doi.org/10.1016/S0920-9964(99)00085-7

Visuospatial working memory in schizotypal personality disorder patients. / Lees Roitman, Sonia E.; Mitropoulou, Vivian; Keefe, Richard S E; Silverman, Jeremy M.; Serby, Michael; Harvey, Philip D; Reynolds, Diedre A.; Mohs, Richard C.; Siever, Larry J.

In: Schizophrenia Research, Vol. 41, No. 3, 14.02.2000, p. 447-455.

Research output: Contribution to journalArticle

Lees Roitman, SE, Mitropoulou, V, Keefe, RSE, Silverman, JM, Serby, M, Harvey, PD, Reynolds, DA, Mohs, RC & Siever, LJ 2000, 'Visuospatial working memory in schizotypal personality disorder patients', Schizophrenia Research, vol. 41, no. 3, pp. 447-455. https://doi.org/10.1016/S0920-9964(99)00085-7
Lees Roitman SE, Mitropoulou V, Keefe RSE, Silverman JM, Serby M, Harvey PD et al. Visuospatial working memory in schizotypal personality disorder patients. Schizophrenia Research. 2000 Feb 14;41(3):447-455. https://doi.org/10.1016/S0920-9964(99)00085-7
Lees Roitman, Sonia E. ; Mitropoulou, Vivian ; Keefe, Richard S E ; Silverman, Jeremy M. ; Serby, Michael ; Harvey, Philip D ; Reynolds, Diedre A. ; Mohs, Richard C. ; Siever, Larry J. / Visuospatial working memory in schizotypal personality disorder patients. In: Schizophrenia Research. 2000 ; Vol. 41, No. 3. pp. 447-455.
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