Virus-associated lymphomas

Ethel Cesarman, Enrique A. Mesri

Research output: Contribution to journalReview article

30 Scopus citations

Abstract

Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8, and human T-cell lymphotrophic virus are viruses that are implicated in lymphoid neoplasia in humans. Their association with specific subsets of lymphomas suggests that they play an important, although not sufficient, etiologic role in their development. Current knowledge suggests that these viruses contribute to lymphomagenesis by subverting the host-cell molecular machinery to deregulate cell growth and survival. In this article, the basic information and recent developments that have contributed to our understanding of viral lymphomagenesis are reviewed.

Original languageEnglish (US)
Pages (from-to)322-332
Number of pages11
JournalCurrent opinion in oncology
Volume11
Issue number5
DOIs
StatePublished - Sep 8 1999
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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