Abstract
As life expectancy continues to rise, elderly adults represent a rapidly growing proportion of the population. The likelihood of complications of acute and chronic liver disease and overall mortality are higher in elderly populations. Several physiological changes associated with aging, greater prevalence of co-morbid conditions, and cumulative exposure to hepatotropic viruses and environmental hepatotoxins may contribute to worse outcomes of viral hepatitis in the elderly. Although pharmacotherapy for hepatitis B and C continues to evolve, the efficacy, tolerability, and side effects of these agents have not been studied extensively in elderly adults. Immunization against hepatitis A and B in naïve elderly adults is an important public health intervention that needs to be revised and broadened.
| Original language | English |
|---|---|
| Pages (from-to) | 691-697 |
| Number of pages | 7 |
| Journal | American Journal of Gastroenterology |
| Volume | 107 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 1 2012 |
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ASJC Scopus subject areas
- Gastroenterology
- Medicine(all)
Cite this
Viral hepatitis in the elderly. / Carrion, Andres F.; Martin, Paul.
In: American Journal of Gastroenterology, Vol. 107, No. 5, 01.05.2012, p. 691-697.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Viral hepatitis in the elderly
AU - Carrion, Andres F.
AU - Martin, Paul
PY - 2012/5/1
Y1 - 2012/5/1
N2 - As life expectancy continues to rise, elderly adults represent a rapidly growing proportion of the population. The likelihood of complications of acute and chronic liver disease and overall mortality are higher in elderly populations. Several physiological changes associated with aging, greater prevalence of co-morbid conditions, and cumulative exposure to hepatotropic viruses and environmental hepatotoxins may contribute to worse outcomes of viral hepatitis in the elderly. Although pharmacotherapy for hepatitis B and C continues to evolve, the efficacy, tolerability, and side effects of these agents have not been studied extensively in elderly adults. Immunization against hepatitis A and B in naïve elderly adults is an important public health intervention that needs to be revised and broadened.
AB - As life expectancy continues to rise, elderly adults represent a rapidly growing proportion of the population. The likelihood of complications of acute and chronic liver disease and overall mortality are higher in elderly populations. Several physiological changes associated with aging, greater prevalence of co-morbid conditions, and cumulative exposure to hepatotropic viruses and environmental hepatotoxins may contribute to worse outcomes of viral hepatitis in the elderly. Although pharmacotherapy for hepatitis B and C continues to evolve, the efficacy, tolerability, and side effects of these agents have not been studied extensively in elderly adults. Immunization against hepatitis A and B in naïve elderly adults is an important public health intervention that needs to be revised and broadened.
UR - http://www.scopus.com/inward/record.url?scp=84862310758&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862310758&partnerID=8YFLogxK
U2 - 10.1038/ajg.2012.7
DO - 10.1038/ajg.2012.7
M3 - Article
C2 - 22290404
AN - SCOPUS:84862310758
VL - 107
SP - 691
EP - 697
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
SN - 0002-9270
IS - 5
ER -