Viral hepatitis

Damien Mallat, Eugene R Schiff

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Viral hepatitis accounts for most liver diseases seen in hepatology practice. In the past year studies have been focused on uncovering the basic mechanisms of viral-cellular interactions, the knowledge of which will contribute to more effective treatment. Hepatitis A virus outbreaks still occur, even in the most developed countries, which points to the need for more comprehensive vaccination measures. Lessons learned from the treatment of HIV with combination antiviral therapies are being applied to both chronic hepatitis B and C. Progress has been made toward better understanding of viral kinetics and the quasispecies of hepatitis C virus with new and more sensitive diagnostic methods. Several therapeutic protocols are emerging to identify and tailor the management approach in various subsets of the population. Although posttransplantation hepatitis B has been more effectively managed with lamivudine therapy, no major advances have been accomplished in the treatment of recurrent hepatitis C among transplant recipients. Major advances in the field of viral hepatitis including A to E and TT viruses during the past year are highlighted.

Original languageEnglish
Pages (from-to)255-261
Number of pages7
JournalCurrent Opinion in Gastroenterology
Volume16
Issue number3
DOIs
StatePublished - Dec 1 2000

Fingerprint

Hepatitis
Therapeutics
Torque teno virus
Hepatitis A virus
Lamivudine
Chronic Hepatitis B
Chronic Hepatitis C
Gastroenterology
Hepatitis C
Hepatitis B
Developed Countries
Hepacivirus
Antiviral Agents
Disease Outbreaks
Liver Diseases
Vaccination
HIV
Population

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Viral hepatitis. / Mallat, Damien; Schiff, Eugene R.

In: Current Opinion in Gastroenterology, Vol. 16, No. 3, 01.12.2000, p. 255-261.

Research output: Contribution to journalArticle

Mallat, Damien ; Schiff, Eugene R. / Viral hepatitis. In: Current Opinion in Gastroenterology. 2000 ; Vol. 16, No. 3. pp. 255-261.
@article{5d207683654b41ce9dd14969adbb0abb,
title = "Viral hepatitis",
abstract = "Viral hepatitis accounts for most liver diseases seen in hepatology practice. In the past year studies have been focused on uncovering the basic mechanisms of viral-cellular interactions, the knowledge of which will contribute to more effective treatment. Hepatitis A virus outbreaks still occur, even in the most developed countries, which points to the need for more comprehensive vaccination measures. Lessons learned from the treatment of HIV with combination antiviral therapies are being applied to both chronic hepatitis B and C. Progress has been made toward better understanding of viral kinetics and the quasispecies of hepatitis C virus with new and more sensitive diagnostic methods. Several therapeutic protocols are emerging to identify and tailor the management approach in various subsets of the population. Although posttransplantation hepatitis B has been more effectively managed with lamivudine therapy, no major advances have been accomplished in the treatment of recurrent hepatitis C among transplant recipients. Major advances in the field of viral hepatitis including A to E and TT viruses during the past year are highlighted.",
author = "Damien Mallat and Schiff, {Eugene R}",
year = "2000",
month = "12",
day = "1",
doi = "10.1097/00001574-200005000-00008",
language = "English",
volume = "16",
pages = "255--261",
journal = "Current Opinion in Gastroenterology",
issn = "0267-1379",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Viral hepatitis

AU - Mallat, Damien

AU - Schiff, Eugene R

PY - 2000/12/1

Y1 - 2000/12/1

N2 - Viral hepatitis accounts for most liver diseases seen in hepatology practice. In the past year studies have been focused on uncovering the basic mechanisms of viral-cellular interactions, the knowledge of which will contribute to more effective treatment. Hepatitis A virus outbreaks still occur, even in the most developed countries, which points to the need for more comprehensive vaccination measures. Lessons learned from the treatment of HIV with combination antiviral therapies are being applied to both chronic hepatitis B and C. Progress has been made toward better understanding of viral kinetics and the quasispecies of hepatitis C virus with new and more sensitive diagnostic methods. Several therapeutic protocols are emerging to identify and tailor the management approach in various subsets of the population. Although posttransplantation hepatitis B has been more effectively managed with lamivudine therapy, no major advances have been accomplished in the treatment of recurrent hepatitis C among transplant recipients. Major advances in the field of viral hepatitis including A to E and TT viruses during the past year are highlighted.

AB - Viral hepatitis accounts for most liver diseases seen in hepatology practice. In the past year studies have been focused on uncovering the basic mechanisms of viral-cellular interactions, the knowledge of which will contribute to more effective treatment. Hepatitis A virus outbreaks still occur, even in the most developed countries, which points to the need for more comprehensive vaccination measures. Lessons learned from the treatment of HIV with combination antiviral therapies are being applied to both chronic hepatitis B and C. Progress has been made toward better understanding of viral kinetics and the quasispecies of hepatitis C virus with new and more sensitive diagnostic methods. Several therapeutic protocols are emerging to identify and tailor the management approach in various subsets of the population. Although posttransplantation hepatitis B has been more effectively managed with lamivudine therapy, no major advances have been accomplished in the treatment of recurrent hepatitis C among transplant recipients. Major advances in the field of viral hepatitis including A to E and TT viruses during the past year are highlighted.

UR - http://www.scopus.com/inward/record.url?scp=0034463252&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034463252&partnerID=8YFLogxK

U2 - 10.1097/00001574-200005000-00008

DO - 10.1097/00001574-200005000-00008

M3 - Article

C2 - 17023883

AN - SCOPUS:0034463252

VL - 16

SP - 255

EP - 261

JO - Current Opinion in Gastroenterology

JF - Current Opinion in Gastroenterology

SN - 0267-1379

IS - 3

ER -