Vertebrate pigmentation: from underlying genes to adaptive function

Joanna K. Hubbard, J. Albert Uy, Mark E. Hauber, Hopi E. Hoekstra, Rebecca J. Safran

Research output: Contribution to journalArticle

188 Citations (Scopus)

Abstract

Animal coloration is a powerful model for studying the genetic mechanisms that determine phenotype. Genetic crosses of laboratory mice have provided extensive information about the patterns of inheritance and pleiotropic effects of loci involved in pigmentation. Recently, the study of pigmentation genes and their functions has extended into wild populations, providing additional evidence that pigment gene function is largely conserved across disparate vertebrate taxa and can influence adaptive coloration, often in predictable ways. These new and integrative studies, along with those using a genetic approach to understand color perception, raise some important questions. Most notably, how does selection shape both phenotypic and genetic variation, and how can we use this information to further understand the phenotypic diversity generated by evolutionary processes?

Original languageEnglish
Pages (from-to)231-239
Number of pages9
JournalTrends in Genetics
Volume26
Issue number5
DOIs
StatePublished - May 1 2010
Externally publishedYes

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Pigmentation
Vertebrates
Genetic Crosses
Color Perception
Inheritance Patterns
Genetic Models
Genes
Phenotype
Population

ASJC Scopus subject areas

  • Genetics

Cite this

Hubbard, J. K., Uy, J. A., Hauber, M. E., Hoekstra, H. E., & Safran, R. J. (2010). Vertebrate pigmentation: from underlying genes to adaptive function. Trends in Genetics, 26(5), 231-239. https://doi.org/10.1016/j.tig.2010.02.002

Vertebrate pigmentation : from underlying genes to adaptive function. / Hubbard, Joanna K.; Uy, J. Albert; Hauber, Mark E.; Hoekstra, Hopi E.; Safran, Rebecca J.

In: Trends in Genetics, Vol. 26, No. 5, 01.05.2010, p. 231-239.

Research output: Contribution to journalArticle

Hubbard, JK, Uy, JA, Hauber, ME, Hoekstra, HE & Safran, RJ 2010, 'Vertebrate pigmentation: from underlying genes to adaptive function', Trends in Genetics, vol. 26, no. 5, pp. 231-239. https://doi.org/10.1016/j.tig.2010.02.002
Hubbard, Joanna K. ; Uy, J. Albert ; Hauber, Mark E. ; Hoekstra, Hopi E. ; Safran, Rebecca J. / Vertebrate pigmentation : from underlying genes to adaptive function. In: Trends in Genetics. 2010 ; Vol. 26, No. 5. pp. 231-239.
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