Vertebral body osteolysis following the use of bone morphogenetic protein in spinal surgery: A mimicker of infection

Gaurav Saigal; Robert Quencer; James D. Guest; Mircea M. Cristescu; Nathan Lebwohl

doi:10.1016/j.neurad.2012.03.005

Vertebral body osteolysis following the use of bone morphogenetic protein in spinal surgery: A mimicker of infection

Gaurav Saigal, Robert Quencer, James D. Guest, Mircea M. Cristescu, Nathan Lebwohl

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

This report describes the imaging findings in three patients who developed lumbar spine osteolysis after posterior spinal fusion using rhBMP-2. These cases demonstrate the variable course of osteolysis, as well as the importance of recognizing its radiological appearances to prevent confusion with infection following spinal fusion.

Original language	English (US)
Pages (from-to)	354-359
Number of pages	6
Journal	Journal of Neuroradiology
Volume	39
Issue number	5
DOIs	https://doi.org/10.1016/j.neurad.2012.03.005
State	Published - Dec 2012

Keywords

BMP
Bone morphogenetic protein
Bone resorption
Cervical spine
Interbody fusion
Lumbar spine
Osteolysis
RhBMP-2

ASJC Scopus subject areas

Clinical Neurology
Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

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10.1016/j.neurad.2012.03.005

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title = "Vertebral body osteolysis following the use of bone morphogenetic protein in spinal surgery: A mimicker of infection",

abstract = "This report describes the imaging findings in three patients who developed lumbar spine osteolysis after posterior spinal fusion using rhBMP-2. These cases demonstrate the variable course of osteolysis, as well as the importance of recognizing its radiological appearances to prevent confusion with infection following spinal fusion.",

keywords = "BMP, Bone morphogenetic protein, Bone resorption, Cervical spine, Interbody fusion, Lumbar spine, Osteolysis, RhBMP-2",

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AU - Guest, James D.

AU - Cristescu, Mircea M.

AU - Lebwohl, Nathan

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AB - This report describes the imaging findings in three patients who developed lumbar spine osteolysis after posterior spinal fusion using rhBMP-2. These cases demonstrate the variable course of osteolysis, as well as the importance of recognizing its radiological appearances to prevent confusion with infection following spinal fusion.

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KW - Bone resorption

KW - Cervical spine

KW - Interbody fusion

KW - Lumbar spine

KW - Osteolysis

KW - RhBMP-2

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Vertebral body osteolysis following the use of bone morphogenetic protein in spinal surgery: A mimicker of infection

Abstract

Keywords

ASJC Scopus subject areas

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