Ventricular tachycardia with alternating cycle lengths: Self-entertainment of parasystolic rhytm?

Agustin Castellanos, I. J. Mendoza, N. Saoudi, J. Jalife

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A patient had ventricular tachycardia with cycle lengths consistently varying between 400 and 490 ms. Arrhythmias with a similar electrocardiographic pattern had been thought to result from the regular activity of an automatic pacemaker with either 3:2 exit block of the Wenckebach type or alternation in exit conduction times. However, the findings in our patient could also be explained by postulating the existence of modulated ventricular parasystole having 3:2 exit block or with alternating (short-long) exit conduction times. In either case, the action potentials elicited by the parasystole must have reached (with variable delays) the ventricular tissue beyond the zone of protection to produce electrotonic depolarizations which, in turn, were reflected back to the ectopic focus itself. This resulted in runs of 2:3 or 2:2 'self-entrainment' of the parasystolic pacemaker. Similar phenomena have been produced in biologic and mathematical models of modulated parasystole.

Original languageEnglish (US)
Pages (from-to)1291-1295
Number of pages5
JournalPACE - Pacing and Clinical Electrophysiology
Volume11
Issue number9
StatePublished - 1988

Fingerprint

Parasystole
Ventricular Tachycardia
Biological Models
Action Potentials
Cardiac Arrhythmias
Theoretical Models

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Ventricular tachycardia with alternating cycle lengths : Self-entertainment of parasystolic rhytm? / Castellanos, Agustin; Mendoza, I. J.; Saoudi, N.; Jalife, J.

In: PACE - Pacing and Clinical Electrophysiology, Vol. 11, No. 9, 1988, p. 1291-1295.

Research output: Contribution to journalArticle

Castellanos, Agustin ; Mendoza, I. J. ; Saoudi, N. ; Jalife, J. / Ventricular tachycardia with alternating cycle lengths : Self-entertainment of parasystolic rhytm?. In: PACE - Pacing and Clinical Electrophysiology. 1988 ; Vol. 11, No. 9. pp. 1291-1295.
@article{051b7c678d264574b3c654235010818c,
title = "Ventricular tachycardia with alternating cycle lengths: Self-entertainment of parasystolic rhytm?",
abstract = "A patient had ventricular tachycardia with cycle lengths consistently varying between 400 and 490 ms. Arrhythmias with a similar electrocardiographic pattern had been thought to result from the regular activity of an automatic pacemaker with either 3:2 exit block of the Wenckebach type or alternation in exit conduction times. However, the findings in our patient could also be explained by postulating the existence of modulated ventricular parasystole having 3:2 exit block or with alternating (short-long) exit conduction times. In either case, the action potentials elicited by the parasystole must have reached (with variable delays) the ventricular tissue beyond the zone of protection to produce electrotonic depolarizations which, in turn, were reflected back to the ectopic focus itself. This resulted in runs of 2:3 or 2:2 'self-entrainment' of the parasystolic pacemaker. Similar phenomena have been produced in biologic and mathematical models of modulated parasystole.",
author = "Agustin Castellanos and Mendoza, {I. J.} and N. Saoudi and J. Jalife",
year = "1988",
language = "English (US)",
volume = "11",
pages = "1291--1295",
journal = "PACE - Pacing and Clinical Electrophysiology",
issn = "0147-8389",
publisher = "Wiley-Blackwell",
number = "9",

}

TY - JOUR

T1 - Ventricular tachycardia with alternating cycle lengths

T2 - Self-entertainment of parasystolic rhytm?

AU - Castellanos, Agustin

AU - Mendoza, I. J.

AU - Saoudi, N.

AU - Jalife, J.

PY - 1988

Y1 - 1988

N2 - A patient had ventricular tachycardia with cycle lengths consistently varying between 400 and 490 ms. Arrhythmias with a similar electrocardiographic pattern had been thought to result from the regular activity of an automatic pacemaker with either 3:2 exit block of the Wenckebach type or alternation in exit conduction times. However, the findings in our patient could also be explained by postulating the existence of modulated ventricular parasystole having 3:2 exit block or with alternating (short-long) exit conduction times. In either case, the action potentials elicited by the parasystole must have reached (with variable delays) the ventricular tissue beyond the zone of protection to produce electrotonic depolarizations which, in turn, were reflected back to the ectopic focus itself. This resulted in runs of 2:3 or 2:2 'self-entrainment' of the parasystolic pacemaker. Similar phenomena have been produced in biologic and mathematical models of modulated parasystole.

AB - A patient had ventricular tachycardia with cycle lengths consistently varying between 400 and 490 ms. Arrhythmias with a similar electrocardiographic pattern had been thought to result from the regular activity of an automatic pacemaker with either 3:2 exit block of the Wenckebach type or alternation in exit conduction times. However, the findings in our patient could also be explained by postulating the existence of modulated ventricular parasystole having 3:2 exit block or with alternating (short-long) exit conduction times. In either case, the action potentials elicited by the parasystole must have reached (with variable delays) the ventricular tissue beyond the zone of protection to produce electrotonic depolarizations which, in turn, were reflected back to the ectopic focus itself. This resulted in runs of 2:3 or 2:2 'self-entrainment' of the parasystolic pacemaker. Similar phenomena have been produced in biologic and mathematical models of modulated parasystole.

UR - http://www.scopus.com/inward/record.url?scp=0024226732&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024226732&partnerID=8YFLogxK

M3 - Article

C2 - 2460833

AN - SCOPUS:0024226732

VL - 11

SP - 1291

EP - 1295

JO - PACE - Pacing and Clinical Electrophysiology

JF - PACE - Pacing and Clinical Electrophysiology

SN - 0147-8389

IS - 9

ER -