Vasopressin: Action on WRK-1 rat mammary tumor cells

M. E. Monaco, P. H. Kohn, W. R. Kidwell, J. S. Strobl, M. E. Lippman

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

WRK-1, a cell line in long-term culture derived from a 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor, responds to physiologic concentrations of vasopressin with increased precursor incorporation into phospholipids and with increased protein accumulation. Because vasopressin has been reported to be a potent mitogen for Hela cells and 3T3 cells, a study was conducted to determine whether it could act as a mitogen for WRK-1 cells. Under no conditions was a clear-cut mitogen response to vasopressin demonstrated.

Original languageEnglish (US)
Pages (from-to)267-270
Number of pages4
JournalJournal of the National Cancer Institute
Volume68
Issue number2
StatePublished - 1982

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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