Varicella zoster virus is a cause of the acute retinal necrosis syndrome

William W Culbertson, M. S. Blumenkranz, J. S. Pepose, J. A. Stewart, V. T. Curtin

Research output: Contribution to journalArticle

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Abstract

We studied two blind eyes enucleated during the active phase of the acute retinal necrosis syndrome. Both eyes showed similar histopathologic findings of necrotizing retinitis, retinal arteritis, and optic neuropathy. A virus morphologically consistent with a herpes group virus was found on electron microscopy and immunocytopathologic stains showed this virus to be varicella zoster in both cases. Varicella zoster virus was cultured from the vitreous of one of the eyes. We conclude that varicella zoster virus retinal infection is a cause of the acute retinal necrosis syndrome.

Original languageEnglish
Pages (from-to)559-569
Number of pages11
JournalOphthalmology
Volume93
Issue number5
StatePublished - Aug 27 1986

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Acute Retinal Necrosis Syndrome
Human Herpesvirus 3
Viruses
Retinitis
Arteritis
Optic Nerve Diseases
Chickenpox
Herpes Zoster
Virus Diseases
Electron Microscopy
Coloring Agents

ASJC Scopus subject areas

  • Ophthalmology

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Culbertson, W. W., Blumenkranz, M. S., Pepose, J. S., Stewart, J. A., & Curtin, V. T. (1986). Varicella zoster virus is a cause of the acute retinal necrosis syndrome. Ophthalmology, 93(5), 559-569.

Varicella zoster virus is a cause of the acute retinal necrosis syndrome. / Culbertson, William W; Blumenkranz, M. S.; Pepose, J. S.; Stewart, J. A.; Curtin, V. T.

In: Ophthalmology, Vol. 93, No. 5, 27.08.1986, p. 559-569.

Research output: Contribution to journalArticle

Culbertson, WW, Blumenkranz, MS, Pepose, JS, Stewart, JA & Curtin, VT 1986, 'Varicella zoster virus is a cause of the acute retinal necrosis syndrome', Ophthalmology, vol. 93, no. 5, pp. 559-569.
Culbertson WW, Blumenkranz MS, Pepose JS, Stewart JA, Curtin VT. Varicella zoster virus is a cause of the acute retinal necrosis syndrome. Ophthalmology. 1986 Aug 27;93(5):559-569.
Culbertson, William W ; Blumenkranz, M. S. ; Pepose, J. S. ; Stewart, J. A. ; Curtin, V. T. / Varicella zoster virus is a cause of the acute retinal necrosis syndrome. In: Ophthalmology. 1986 ; Vol. 93, No. 5. pp. 559-569.
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