Variations in patent foramen ovale size in a patient with pulmonary emboli: A transesophageal echocardiographic assessment

F. Sam, D. W. Leibowitz, M. R. Di Tullio, Ralph L Sacco, S. Homma

Research output: Contribution to journalArticle


Patent foramen ovale has been associated with paradoxical embolism. The size of the patent foramen ovale, and hence the degree of shunting, can vary with changes in hemodynamics. We report the case of a patient with a large patent foramen ovale documented by transesophageal echocardiography in the setting of a pulmonary embolus and paradoxical embolism which nearly resolved after anticoagulation. In the setting of elevated right atrial pressures, a patent foramen ovale that may be insignificant at baseline may open widely and serve as a conduit for paradoxical embolism. Optimal therapy for patent foramen ovale associated with paradoxical embolism remains unclear but should include anticoagulation with consideration of surgical closure in patients with recurrent events on therapy.

Original languageEnglish
Pages (from-to)55-59
Number of pages5
JournalCardiovascular Reviews and Reports
Issue number8
StatePublished - Jan 1 1995
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this