Abstract
We review the history of vancomycin-resistant enterococci (VRE) and propose a causal model illustrating the roles of exposure to VRE reservoirs, patient characteristics, antimicrobial exposure, and prevalence of VRE in the progression from potential VRE reservoirs to active disease in hospitalized patients. Differences in VRE colonization and VRE infection are discussed with respect to hospital surveillance methodology and implications for interventions. We further document clonal transmission of VRE in a large, urban, teaching hospital and demonstrate VRE susceptibility to a wide array of antimicrobial agents. This model can guide the identification of mutable factors that are focal points for intervention.
| Original language | English |
|---|---|
| Pages (from-to) | 159-171 |
| Number of pages | 13 |
| Journal | Journal of Hospital Infection |
| Volume | 53 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2003 |
| Externally published | Yes |
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Keywords
- Antimicrobials
- Enterococci
- Resistance
- Vancomycin
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology
- Microbiology
- Parasitology
- Virology
- Immunology and Allergy
- Infectious Diseases
Cite this
Vancomycin-resistant enterococci : 15 years and counting. / Chavers, L. S.; Moser, S. A.; Benjamin, W. H.; Banks, Shawn; Steinhauer, J. R.; Smith, A. M.; Johnson, C. N.; Funkhouser, E.; Chavers, L. P.; Stamm, A. M.; Waites, Ken B.
In: Journal of Hospital Infection, Vol. 53, No. 3, 01.03.2003, p. 159-171.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Vancomycin-resistant enterococci
T2 - 15 years and counting
AU - Chavers, L. S.
AU - Moser, S. A.
AU - Benjamin, W. H.
AU - Banks, Shawn
AU - Steinhauer, J. R.
AU - Smith, A. M.
AU - Johnson, C. N.
AU - Funkhouser, E.
AU - Chavers, L. P.
AU - Stamm, A. M.
AU - Waites, Ken B.
PY - 2003/3/1
Y1 - 2003/3/1
N2 - We review the history of vancomycin-resistant enterococci (VRE) and propose a causal model illustrating the roles of exposure to VRE reservoirs, patient characteristics, antimicrobial exposure, and prevalence of VRE in the progression from potential VRE reservoirs to active disease in hospitalized patients. Differences in VRE colonization and VRE infection are discussed with respect to hospital surveillance methodology and implications for interventions. We further document clonal transmission of VRE in a large, urban, teaching hospital and demonstrate VRE susceptibility to a wide array of antimicrobial agents. This model can guide the identification of mutable factors that are focal points for intervention.
AB - We review the history of vancomycin-resistant enterococci (VRE) and propose a causal model illustrating the roles of exposure to VRE reservoirs, patient characteristics, antimicrobial exposure, and prevalence of VRE in the progression from potential VRE reservoirs to active disease in hospitalized patients. Differences in VRE colonization and VRE infection are discussed with respect to hospital surveillance methodology and implications for interventions. We further document clonal transmission of VRE in a large, urban, teaching hospital and demonstrate VRE susceptibility to a wide array of antimicrobial agents. This model can guide the identification of mutable factors that are focal points for intervention.
KW - Antimicrobials
KW - Enterococci
KW - Resistance
KW - Vancomycin
UR - http://www.scopus.com/inward/record.url?scp=0038312007&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038312007&partnerID=8YFLogxK
U2 - 10.1053/jhin.2002.1375
DO - 10.1053/jhin.2002.1375
M3 - Article
C2 - 12623315
AN - SCOPUS:0038312007
VL - 53
SP - 159
EP - 171
JO - Journal of Hospital Infection
JF - Journal of Hospital Infection
SN - 0195-6701
IS - 3
ER -