Validation of a European Spanish-version of the University of California performance Skills Assessment (Sp-UPSA) in patients with schizophrenia and bipolar disorder

Maria P. Garcia-Portilla, Jesus J. Gomar, Maria T. Bobes-Bascaran, Isabel Menendez-Miranda, Pilar A. Saiz, Jose Muñiz, Celso Arango, Thomas L. Patterson, Philip D. Harvey, Julio Bobes, Terry E. Goldberg

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Aims: To validate the Spanish version of the University of California Performance Skills Assessment (UPSA) in patients with severe mental disorders. Methods: Naturalistic, 6. month follow-up, multicentre, validation study. 139 patients with schizophrenia, 57 bipolar patients and 31 controls were evaluated using the following scales: Spanish UPSA (Sp-UPSA), Clinical Global Impression, Severity (CGI-S), Global Assessment of Functioning (GAF), and Personal and Social Performance (PSP). Results: Reliability: Internal consistency (Cronbach's alpha) was 0.81 in schizophrenia and 0.58 in bipolar patients. Test-retest was 0.74 and 0.65 (p< 0.0001) respectively. Construct validity: Pearson correlation coefficients between Sp-UPSA and PSP total scores were 0.42 (p< 0.0001) for schizophrenia and 0.44 (p= 0.001) for bipolar patients. For Sp-UPSA and GAF scores correlation coefficients were 0.43 and 0.52 (p< 0.0001) respectively. Discriminant validity: The Sp-UPSA discriminated between patients and controls. In schizophrenia patients it also discriminated among different levels of illness severity according to CGI-S scores. In control versus patients with schizophrenia contrasts, the area under the curve was 0.89 and a cut-off point of 85 provided a sensitivity of 82.7% and a specificity of 77.4%. In bipolar patients, the area under the curve was 0.85 and a cut-off point of 90 provided a sensitivity of 82.5% and a specificity of 64.5%. Conclusion: The Spanish UPSA is a reliable and valid instrument for assessing functional capacity in severe mentally ill patients. It seems to be appropriate for use in clinical trials and in everyday clinical practice as a means of monitoring functional outcomes.

Original languageEnglish (US)
Pages (from-to)421-426
Number of pages6
JournalSchizophrenia Research
Volume150
Issue number2-3
DOIs
StatePublished - Nov 1 2013

Keywords

  • Bipolar disorder
  • Functional capacity
  • Psychometric properties
  • Schizophrenia
  • Sp-UPSA

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Fingerprint Dive into the research topics of 'Validation of a European Spanish-version of the University of California performance Skills Assessment (Sp-UPSA) in patients with schizophrenia and bipolar disorder'. Together they form a unique fingerprint.

  • Cite this

    Garcia-Portilla, M. P., Gomar, J. J., Bobes-Bascaran, M. T., Menendez-Miranda, I., Saiz, P. A., Muñiz, J., Arango, C., Patterson, T. L., Harvey, P. D., Bobes, J., & Goldberg, T. E. (2013). Validation of a European Spanish-version of the University of California performance Skills Assessment (Sp-UPSA) in patients with schizophrenia and bipolar disorder. Schizophrenia Research, 150(2-3), 421-426. https://doi.org/10.1016/j.schres.2013.07.049