Vaginal recurrence of adenocarcinoma of the endometrium

George L. Phillips, Konald A. Prem, Leon L. Adcock, Leo B. Twiggs

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


During a 28-year period, 949 patients were treated for adenocarcinoma of the endometrium at the University of Minnesota Hospitals. Eighty-one of these patients presented with vaginal recurrence. The incidence of vaginal recurrence for patients receiving primary therapy at this institution was 0.9%. Sixty-nine percent of patients presented with vaginal bleeding, but 22% were asymptomatic. Seventy-three percent of patients eventually died of disease. Seventy-five percent of recurrences occurred within 3 years of primary therapy, but much longer intervals were noted. In patients with isolated vaginal recurrences, the interval to recurrence directly correlated with survival (P < 0.0005). The poor outcome of these patients indicates a need for evaluation of adjuvant therapy.

Original languageEnglish (US)
Pages (from-to)323-328
Number of pages6
JournalGynecologic oncology
Issue number3
StatePublished - Jun 1982

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology


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