UTIs in Patients with Neurogenic Bladder

Mona S. Jahromi, Amanda Mure, Christopher Gomez

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Urinary tract infections (UTI) remain one of the most prevalent and frustrating morbidities for neurogenic bladder patients, and death attributed to urosepsis in the spinal cord injury (SCI) patient is higher when compared to the general population. Risk factors include urinary stasis, high bladder pressures, bladder stones, and catheter use. While classic symptoms of UTI include dysuria, increased frequency and urgency, neurogenic bladder patients present differently with increased spasticity, autonomic dysreflexia, urinary incontinence, and vague pains. Multiple modalities have been assessed for prevention including catheter type, oral supplements, bladder irrigation, detrusor injections and prophylactic antimicrobials. Of these, bladder inoculation with E. coli HU2117, irrigation with iAluRil®, detrusor injections, and weekly prophylaxis with alternating antibiotics appear to have a positive reduction in UTI but require further study. Ultimately, treatment for symptomatic UTI should account for the varied flora and possible antibiotic resistances including relying on urine cultures to guide antibiotic therapy.

Original languageEnglish (US)
Article number433
Pages (from-to)1-7
Number of pages7
JournalCurrent Urology Reports
Volume15
Issue number9
DOIs
StatePublished - Sep 1 2014

Keywords

  • Clean intermittent catheterization
  • Multiple sclerosis
  • Neurogenic bladder
  • Spinal cord injury
  • Urinary tract infection
  • UTI prophylaxis

ASJC Scopus subject areas

  • Urology

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