Utilization of deceased donors during a pandemic: argument against using SARS-CoV-2–positive donors

Malay B. Shah, Raymond J. Lynch, Hanine El-Haddad, Brianna Doby, Diane Brockmeier, David S. Goldberg

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become an unprecedented pandemic that has impacted society, disrupted hospital functions, strained health care resources, and impacted the lives of transplant professionals. Despite this, organ failure and the need for transplant continues throughout the United States. Considering the perpetual scarcity of deceased donor organs, Kates et al present a viewpoint that advocates for the utilization of coronavirus disease 2019 (COVID-19)–positive donors in selected cases. We present a review of the current literature that details the potential negative consequences of COVID-19–positive donors. The factors we consider include (1) the risk of blood transmission of SARS-CoV-2, (2) involvement of donor organs, (3) lack of effective therapies, (4) exposure of health care and recovery teams, (5) disease transmission and propagation, and (6) hospital resource utilization. While we acknowledge that transplant fulfills the mission of saving lives, it is imperative to consider the consequences not only to our recipients but also to the community and to health care workers, particularly in the absence of effective preventative or curative therapies. For these reasons, we believe the evidence and risks show that COVID-19 infection should continue to remain a contraindication for donation, as has been the initial response of donation and transplant societies.

Original languageEnglish (US)
Pages (from-to)1795-1799
Number of pages5
JournalAmerican Journal of Transplantation
Volume20
Issue number7
DOIs
StatePublished - Jul 1 2020

Keywords

  • donors and donation
  • editorial/personal viewpoint
  • ethics and public policy
  • infection and infectious agents – viral
  • infectious disease
  • organ allocation
  • organ procurement
  • organ procurement and allocation
  • organ transplantation in general

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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