Usual and unusual radiologic manifestations of acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection in children

B. F. Bradford, G. E. Abdenour, J. L. Frank, Gwendolyn B Scott, R. Beerman

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

HIV infection in children has a uniformly poor prognosis, as it does in adults. As the number of cases in children increases, the incidence of grave complications such as Kaposi sarcoma and opportunistic central nervous system infection may approach the level seen in adults. There remains no cure and even the development of a vaccine may take years of further research. Antifungal and antiprotozoan drugs have had limited success in the symptomatic treatment of these patients. Presently the best hope for significant prolongation of life lies in drugs such as azidothymidine (AZT), which act to interfere with viral replication and its resultant lymphocyte destruction. Prompt diagnosis of the disease can, at least, lead to an improved short-term prognosis. Drug therapy as well as counseling must be instituted as soon as possible. It is therefore of some importance that the level of suspicion be heightened among all physicians, including the general and pediatric radiologist. Although many of the radiologic findings described in this report are nonspecific, certain abnormalities should increase the concern of radiologists, particularly in young infants with the appropriate history and physical findings. These include (1) diffuse esophagitis, (2) rapidly progressive diffuse pulmonary consolidation, (3) diffuse reticulonodular pulmonary infiltrates, (4) intra-abdominal adenopathy, and (5) large intra-abdominal masses not related to the kidney, adrenal gland, or liver.

Original languageEnglish
Pages (from-to)341-353
Number of pages13
JournalRadiologic Clinics of North America
Volume26
Issue number2
StatePublished - Jan 1 1988

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Virus Diseases
Acquired Immunodeficiency Syndrome
HIV
Life Support Care
Central Nervous System Infections
Lung
Esophagitis
Zidovudine
Kaposi's Sarcoma
Adrenal Glands
Pharmaceutical Preparations
Counseling
Vaccines
History
Lymphocytes
Pediatrics
Physicians
Kidney
Drug Therapy
Liver

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Usual and unusual radiologic manifestations of acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection in children. / Bradford, B. F.; Abdenour, G. E.; Frank, J. L.; Scott, Gwendolyn B; Beerman, R.

In: Radiologic Clinics of North America, Vol. 26, No. 2, 01.01.1988, p. 341-353.

Research output: Contribution to journalArticle

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