Abstract
The objective of this study was to examine the sensitivity and specificity of a performance-based measure of functional capacity, the UCSD Performance-based Skills Assessment (UPSA), for the prediction of independent living status in patients with chronic schizophrenia-related conditions. A sample of 434 adults with schizophrenia or schizoaffective disorder was administered the UPSA and assessed for independent living status. Participants were classified as "independent" if they were living alone in an apartment, house, or single-resident occupancy (e.g., hotel room) and non-independent if they resided in a care facility (e.g., Board-and-Care home, Skilled Nursing Facility). Receiver Operator Characteristic (ROC) curves were calculated with the UPSA and Mattis' Dementia Rating Scale (DRS) scores as predictor variables and residential independence as the state variable. Of the 434 participants, 99 (23%) were living independently at the time of assessment. The discriminant validity of the UPSA was adequate (ROC area under the curve = 0.74; 95% CI: 0.68-0.79), with greatest dichotomization for the UPSA at a cutoff score of 75 (68% accuracy, 69% sensitivity, 66% specificity), or 80 (68% accuracy, 59% sensitivity, 76% specificity). The UPSA was also a significantly better predictor of living status than was the DRS, based on ROC (z = 2.43, p = .015). The UPSA is a brief measure of functional capacity that predicts the ability of patients with schizophrenia to reside independently in the community.
| Original language | English |
|---|---|
| Pages (from-to) | 320-327 |
| Number of pages | 8 |
| Journal | Journal of Psychiatric Research |
| Volume | 42 |
| Issue number | 4 |
| DOIs | |
| State | Published - Mar 1 2008 |
| Externally published | Yes |
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Keywords
- Cognitive function
- Functional outcomes
- Independence
- Schizophrenia
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
- Psychology(all)
Cite this
Usefulness of the UCSD performance-based skills assessment (UPSA) for predicting residential independence in patients with chronic schizophrenia. / Mausbach, Brent T.; Bowie, Christopher R.; Harvey, Philip D; Twamley, Elizabeth W.; Goldman, Sherrill R.; Jeste, Dilip V.; Patterson, Thomas L.
In: Journal of Psychiatric Research, Vol. 42, No. 4, 01.03.2008, p. 320-327.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Usefulness of the UCSD performance-based skills assessment (UPSA) for predicting residential independence in patients with chronic schizophrenia
AU - Mausbach, Brent T.
AU - Bowie, Christopher R.
AU - Harvey, Philip D
AU - Twamley, Elizabeth W.
AU - Goldman, Sherrill R.
AU - Jeste, Dilip V.
AU - Patterson, Thomas L.
PY - 2008/3/1
Y1 - 2008/3/1
N2 - The objective of this study was to examine the sensitivity and specificity of a performance-based measure of functional capacity, the UCSD Performance-based Skills Assessment (UPSA), for the prediction of independent living status in patients with chronic schizophrenia-related conditions. A sample of 434 adults with schizophrenia or schizoaffective disorder was administered the UPSA and assessed for independent living status. Participants were classified as "independent" if they were living alone in an apartment, house, or single-resident occupancy (e.g., hotel room) and non-independent if they resided in a care facility (e.g., Board-and-Care home, Skilled Nursing Facility). Receiver Operator Characteristic (ROC) curves were calculated with the UPSA and Mattis' Dementia Rating Scale (DRS) scores as predictor variables and residential independence as the state variable. Of the 434 participants, 99 (23%) were living independently at the time of assessment. The discriminant validity of the UPSA was adequate (ROC area under the curve = 0.74; 95% CI: 0.68-0.79), with greatest dichotomization for the UPSA at a cutoff score of 75 (68% accuracy, 69% sensitivity, 66% specificity), or 80 (68% accuracy, 59% sensitivity, 76% specificity). The UPSA was also a significantly better predictor of living status than was the DRS, based on ROC (z = 2.43, p = .015). The UPSA is a brief measure of functional capacity that predicts the ability of patients with schizophrenia to reside independently in the community.
AB - The objective of this study was to examine the sensitivity and specificity of a performance-based measure of functional capacity, the UCSD Performance-based Skills Assessment (UPSA), for the prediction of independent living status in patients with chronic schizophrenia-related conditions. A sample of 434 adults with schizophrenia or schizoaffective disorder was administered the UPSA and assessed for independent living status. Participants were classified as "independent" if they were living alone in an apartment, house, or single-resident occupancy (e.g., hotel room) and non-independent if they resided in a care facility (e.g., Board-and-Care home, Skilled Nursing Facility). Receiver Operator Characteristic (ROC) curves were calculated with the UPSA and Mattis' Dementia Rating Scale (DRS) scores as predictor variables and residential independence as the state variable. Of the 434 participants, 99 (23%) were living independently at the time of assessment. The discriminant validity of the UPSA was adequate (ROC area under the curve = 0.74; 95% CI: 0.68-0.79), with greatest dichotomization for the UPSA at a cutoff score of 75 (68% accuracy, 69% sensitivity, 66% specificity), or 80 (68% accuracy, 59% sensitivity, 76% specificity). The UPSA was also a significantly better predictor of living status than was the DRS, based on ROC (z = 2.43, p = .015). The UPSA is a brief measure of functional capacity that predicts the ability of patients with schizophrenia to reside independently in the community.
KW - Cognitive function
KW - Functional outcomes
KW - Independence
KW - Schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=38849164867&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38849164867&partnerID=8YFLogxK
U2 - 10.1016/j.jpsychires.2006.12.008
DO - 10.1016/j.jpsychires.2006.12.008
M3 - Article
C2 - 17303168
AN - SCOPUS:38849164867
VL - 42
SP - 320
EP - 327
JO - Journal of Psychiatric Research
JF - Journal of Psychiatric Research
SN - 0022-3956
IS - 4
ER -