Background: Mixed results are reported for procalcitonin (PCT) as biomarkers of infection and disease activity in inflammatory bowel disease (IBD). Method: We systematically evaluated and performed a meta-analysis on the usefulness of PCT in assessing infection and disease activity in IBD. Results: The pooled standardized mean difference of PCT for those with infection compared with those without was 1.59 (95% CI, 0.72-2.46, P < 0.01) and those with active disease compared with those without was 1.22 (95% CI, 0.66-1.78, P < 0.01), respectively. Conclusion: PCT may potentially be useful in differentiating an infectious process from IBD and active from inactive IBD.
- Ulcerative colitis
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