Use of Umbilical Cord Blood for Stem Cell Research

Sylvie Bordet, Thu Minh Nguyen, Bartha Maria Knoppers, Rosario Isasi

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Umbilical cord blood (UCB), long treated as waste material, is today considered a valuable source of hematopoietic stem cells. UCB is used, mostly in children, for the treatment of blood malignancies and inherited blood and metabolic disorders. In addition to blood precursor cells, UCB also contains stem cells that can differentiate into other types, such as cartilage, fat, hepatic, cardiac, and neural cells, fuelling speculation about the use of cord blood stem cells for regenerative medicine. Further research is therefore needed to investigate the expanded potential of UCB and its therapeutic use in cell and tissue therapies. According to a recent survey, practices for the procurement of UCB for research vary widely across Canada, so this area may not yet be ready for uniform regulation. However, some harmonization of practices to increase the availability of UCB for research would be useful for Canadian investigators. In this article, we address several important ethical and legal issues relating to the use of UCB in research and recommend guidelines to serve as a source of useful information for researchers. While their legal acceptability may vary across Canada, it is hoped that these recommendations foster more harmonized UCB research practices.

Original languageEnglish (US)
Pages (from-to)58-61
Number of pages4
JournalJournal of Obstetrics and Gynaecology Canada
Volume32
Issue number1
DOIs
StatePublished - Jan 1 2010
Externally publishedYes

Keywords

  • Ethical issues
  • Legal issues
  • Research
  • Umbilical cord blood

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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