Abstract
In this study we examined the ability of tumour specimens derived from bladder barbotage to produce cluster/colony formation in a tumour colony assay. In 114 bladder washings from 65 patients and 15 control subjects, we found that cluster and colony formation was highest from bladder washings obtained from patients with biopsy proven bladder cancer who were not on intravesical chemotherapy. Growth rates were extremely low, restricting the usefulness of the in vitro assay in its present form. This study suggests that improvements in the growth rates in the tumour colony assay will be necessary before this system can have real value in monitoring transitional cell carcinoma of the bladder
| Original language | English |
|---|---|
| Pages (from-to) | 271-274 |
| Number of pages | 4 |
| Journal | British Journal of Urology |
| Volume | 55 |
| Issue number | 3 |
| State | Published - Jan 1 1983 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Urology
Cite this
Use of the tumour colony assay in the evaluation of patients with bladder cancer. / Niell, H. B.; Soloway, M. S.
In: British Journal of Urology, Vol. 55, No. 3, 01.01.1983, p. 271-274.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Use of the tumour colony assay in the evaluation of patients with bladder cancer
AU - Niell, H. B.
AU - Soloway, M. S.
PY - 1983/1/1
Y1 - 1983/1/1
N2 - In this study we examined the ability of tumour specimens derived from bladder barbotage to produce cluster/colony formation in a tumour colony assay. In 114 bladder washings from 65 patients and 15 control subjects, we found that cluster and colony formation was highest from bladder washings obtained from patients with biopsy proven bladder cancer who were not on intravesical chemotherapy. Growth rates were extremely low, restricting the usefulness of the in vitro assay in its present form. This study suggests that improvements in the growth rates in the tumour colony assay will be necessary before this system can have real value in monitoring transitional cell carcinoma of the bladder
AB - In this study we examined the ability of tumour specimens derived from bladder barbotage to produce cluster/colony formation in a tumour colony assay. In 114 bladder washings from 65 patients and 15 control subjects, we found that cluster and colony formation was highest from bladder washings obtained from patients with biopsy proven bladder cancer who were not on intravesical chemotherapy. Growth rates were extremely low, restricting the usefulness of the in vitro assay in its present form. This study suggests that improvements in the growth rates in the tumour colony assay will be necessary before this system can have real value in monitoring transitional cell carcinoma of the bladder
UR - http://www.scopus.com/inward/record.url?scp=0020604272&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020604272&partnerID=8YFLogxK
M3 - Article
C2 - 6342702
AN - SCOPUS:0020604272
VL - 55
SP - 271
EP - 274
JO - BJU International
JF - BJU International
SN - 1464-4096
IS - 3
ER -