Use of pediatric donor en bloc kidneys along with bladder segment in pediatric liver-kidney and multivisceral-kidney transplantation

Filipe Kunzler de Oliveira Maia, Akin Tekin, Ramona Nicolau-Raducu, Thiago Beduschi, Gennaro Selvaggi, Rodrigo Vianna, Mohamad Ammar Al Nuss, Javier González, Jeffrey J. Gaynor, Gaetano Ciancio

Research output: Contribution to journalArticle

Abstract

The combination of pediatric multivisceral and kidney transplantation leads to additional recipient risks due to the number of anastomoses and to the small sizes of donor structures. The inclusion of donor kidneys, ureters, and a bladder patch en bloc with multivisceral organs decreases the number and complexity of anastomoses and has not yet been reported. Four patients were transplanted in this fashion; three underwent multivisceral-kidney and one underwent liver-kidney transplantation. The first patient was a 3-year-old male with polycystic kidney disease and congenital hepatic fibrosis. The second was a 7-year-old female with complications from necrotizing enterocolitis. The third was a 12-month-old male with megacystis microcolon intestinal hypoperistalsis syndrome and secondary hydronephrosis, and the fourth was a 3-year-old male with multiple intestinal resections secondary to incarcerated hernia. The third patient developed a right ureteral stenosis with an intact bladder patch. The fourth child expired from maintained abdominal sepsis. The first 3 patients maintained normal graft function. There were no cases of thrombosis, arterial stenosis, or urinary leakages. These reported cases demonstrate that small pediatric en bloc transplantation of the multivisceral organs and dual kidneys with a bladder patch anastomosis is a feasible and less complex alternative to the standard procedure.

Original languageEnglish (US)
Article numbere13596
JournalPediatric Transplantation
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Kidney Transplantation
Urinary Bladder
Tissue Donors
Pediatrics
Kidney
Liver
Pathologic Constriction
Polycystic Kidney Diseases
Necrotizing Enterocolitis
Hydronephrosis
Organ Transplantation
Ureter
Hernia
Liver Transplantation
Sepsis
Thrombosis
Transplants

Keywords

  • bladder patch technique
  • bladder patch transplantation
  • en bloc transplantation
  • kidney transplantation
  • liver transplantation
  • multivisceral transplantation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

Cite this

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title = "Use of pediatric donor en bloc kidneys along with bladder segment in pediatric liver-kidney and multivisceral-kidney transplantation",
abstract = "The combination of pediatric multivisceral and kidney transplantation leads to additional recipient risks due to the number of anastomoses and to the small sizes of donor structures. The inclusion of donor kidneys, ureters, and a bladder patch en bloc with multivisceral organs decreases the number and complexity of anastomoses and has not yet been reported. Four patients were transplanted in this fashion; three underwent multivisceral-kidney and one underwent liver-kidney transplantation. The first patient was a 3-year-old male with polycystic kidney disease and congenital hepatic fibrosis. The second was a 7-year-old female with complications from necrotizing enterocolitis. The third was a 12-month-old male with megacystis microcolon intestinal hypoperistalsis syndrome and secondary hydronephrosis, and the fourth was a 3-year-old male with multiple intestinal resections secondary to incarcerated hernia. The third patient developed a right ureteral stenosis with an intact bladder patch. The fourth child expired from maintained abdominal sepsis. The first 3 patients maintained normal graft function. There were no cases of thrombosis, arterial stenosis, or urinary leakages. These reported cases demonstrate that small pediatric en bloc transplantation of the multivisceral organs and dual kidneys with a bladder patch anastomosis is a feasible and less complex alternative to the standard procedure.",
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author = "{Kunzler de Oliveira Maia}, Filipe and Akin Tekin and Ramona Nicolau-Raducu and Thiago Beduschi and Gennaro Selvaggi and Rodrigo Vianna and {Ammar Al Nuss}, Mohamad and Javier Gonz{\'a}lez and Gaynor, {Jeffrey J.} and Gaetano Ciancio",
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T1 - Use of pediatric donor en bloc kidneys along with bladder segment in pediatric liver-kidney and multivisceral-kidney transplantation

AU - Kunzler de Oliveira Maia, Filipe

AU - Tekin, Akin

AU - Nicolau-Raducu, Ramona

AU - Beduschi, Thiago

AU - Selvaggi, Gennaro

AU - Vianna, Rodrigo

AU - Ammar Al Nuss, Mohamad

AU - González, Javier

AU - Gaynor, Jeffrey J.

AU - Ciancio, Gaetano

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