Abstract
The combination of pediatric multivisceral and kidney transplantation leads to additional recipient risks due to the number of anastomoses and to the small sizes of donor structures. The inclusion of donor kidneys, ureters, and a bladder patch en bloc with multivisceral organs decreases the number and complexity of anastomoses and has not yet been reported. Four patients were transplanted in this fashion; three underwent multivisceral-kidney and one underwent liver-kidney transplantation. The first patient was a 3-year-old male with polycystic kidney disease and congenital hepatic fibrosis. The second was a 7-year-old female with complications from necrotizing enterocolitis. The third was a 12-month-old male with megacystis microcolon intestinal hypoperistalsis syndrome and secondary hydronephrosis, and the fourth was a 3-year-old male with multiple intestinal resections secondary to incarcerated hernia. The third patient developed a right ureteral stenosis with an intact bladder patch. The fourth child expired from maintained abdominal sepsis. The first 3 patients maintained normal graft function. There were no cases of thrombosis, arterial stenosis, or urinary leakages. These reported cases demonstrate that small pediatric en bloc transplantation of the multivisceral organs and dual kidneys with a bladder patch anastomosis is a feasible and less complex alternative to the standard procedure.
| Original language | English (US) |
|---|---|
| Article number | e13596 |
| Journal | Pediatric Transplantation |
| DOIs | |
| State | Accepted/In press - Jan 1 2019 |
Fingerprint
Keywords
- bladder patch technique
- bladder patch transplantation
- en bloc transplantation
- kidney transplantation
- liver transplantation
- multivisceral transplantation
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Transplantation
Cite this
Use of pediatric donor en bloc kidneys along with bladder segment in pediatric liver-kidney and multivisceral-kidney transplantation. / Kunzler de Oliveira Maia, Filipe; Tekin, Akin; Nicolau-Raducu, Ramona; Beduschi, Thiago; Selvaggi, Gennaro; Vianna, Rodrigo; Ammar Al Nuss, Mohamad; González, Javier; Gaynor, Jeffrey J.; Ciancio, Gaetano.
In: Pediatric Transplantation, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Use of pediatric donor en bloc kidneys along with bladder segment in pediatric liver-kidney and multivisceral-kidney transplantation
AU - Kunzler de Oliveira Maia, Filipe
AU - Tekin, Akin
AU - Nicolau-Raducu, Ramona
AU - Beduschi, Thiago
AU - Selvaggi, Gennaro
AU - Vianna, Rodrigo
AU - Ammar Al Nuss, Mohamad
AU - González, Javier
AU - Gaynor, Jeffrey J.
AU - Ciancio, Gaetano
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The combination of pediatric multivisceral and kidney transplantation leads to additional recipient risks due to the number of anastomoses and to the small sizes of donor structures. The inclusion of donor kidneys, ureters, and a bladder patch en bloc with multivisceral organs decreases the number and complexity of anastomoses and has not yet been reported. Four patients were transplanted in this fashion; three underwent multivisceral-kidney and one underwent liver-kidney transplantation. The first patient was a 3-year-old male with polycystic kidney disease and congenital hepatic fibrosis. The second was a 7-year-old female with complications from necrotizing enterocolitis. The third was a 12-month-old male with megacystis microcolon intestinal hypoperistalsis syndrome and secondary hydronephrosis, and the fourth was a 3-year-old male with multiple intestinal resections secondary to incarcerated hernia. The third patient developed a right ureteral stenosis with an intact bladder patch. The fourth child expired from maintained abdominal sepsis. The first 3 patients maintained normal graft function. There were no cases of thrombosis, arterial stenosis, or urinary leakages. These reported cases demonstrate that small pediatric en bloc transplantation of the multivisceral organs and dual kidneys with a bladder patch anastomosis is a feasible and less complex alternative to the standard procedure.
AB - The combination of pediatric multivisceral and kidney transplantation leads to additional recipient risks due to the number of anastomoses and to the small sizes of donor structures. The inclusion of donor kidneys, ureters, and a bladder patch en bloc with multivisceral organs decreases the number and complexity of anastomoses and has not yet been reported. Four patients were transplanted in this fashion; three underwent multivisceral-kidney and one underwent liver-kidney transplantation. The first patient was a 3-year-old male with polycystic kidney disease and congenital hepatic fibrosis. The second was a 7-year-old female with complications from necrotizing enterocolitis. The third was a 12-month-old male with megacystis microcolon intestinal hypoperistalsis syndrome and secondary hydronephrosis, and the fourth was a 3-year-old male with multiple intestinal resections secondary to incarcerated hernia. The third patient developed a right ureteral stenosis with an intact bladder patch. The fourth child expired from maintained abdominal sepsis. The first 3 patients maintained normal graft function. There were no cases of thrombosis, arterial stenosis, or urinary leakages. These reported cases demonstrate that small pediatric en bloc transplantation of the multivisceral organs and dual kidneys with a bladder patch anastomosis is a feasible and less complex alternative to the standard procedure.
KW - bladder patch technique
KW - bladder patch transplantation
KW - en bloc transplantation
KW - kidney transplantation
KW - liver transplantation
KW - multivisceral transplantation
UR - http://www.scopus.com/inward/record.url?scp=85074052920&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85074052920&partnerID=8YFLogxK
U2 - 10.1111/petr.13596
DO - 10.1111/petr.13596
M3 - Article
C2 - 31605438
AN - SCOPUS:85074052920
JO - Pediatric Transplantation
JF - Pediatric Transplantation
SN - 1397-3142
M1 - e13596
ER -