Use of medical foods and nutritional approaches in the treatment of Alzheimer's disease

Papan Thaipisuttikul, James E. Galvin

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations

Abstract

Alzheimer's disease, the most common cause of dementia, has a high global economic impact. To date, there is no curative treatment; therefore, many efforts are directed not only at novel potential disease-modifying treatments and interventions, but also to develop alternative symptomatic and supportive treatments. Examples of these efforts include the medical foods. There are three medical foods that claim to offer symptomatic benefits: Axona®, Souvenaid® and CerefolinNAC®. Axona supplies ketone bodies as alternative energy source to neurons. Souvenaid provides precursors thought to enhance synaptic function. CerefolinNAC addresses the role of oxidative stress related to memory loss. The current scientific evidence on these medical foods is reviewed in this article. Furthermore, we also review the concept and evidence supporting use of the Mediterranean diet, a possible alternative to medical foods that, if implemented correctly, may have lower costs, fewer side effects and stronger epidemiological health outcomes.

Original languageEnglish (US)
Pages (from-to)199-209
Number of pages11
JournalClinical Practice
Volume9
Issue number2
DOIs
StatePublished - Mar 2012
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology (medical)

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