Introduction Polyneuropathy in critically-ill patients (PPC) accounts for 50-70% of septic patients, is sensory, motor, axonal, acute in nature, and has been related to increased morbidity and mortality. Patients and methods A cross-sectional, observational study, conducted between May 2015 and May 2016 at Sanatorio Allende in Córdoba, Argentina. Patients with diagnosis of sepsis who received electrophysiological examination between Day 3 and Day 7 of a diagnosis of sepsis in order to make an early diagnosis of PPC were included in this study. Results Out of the 1,176 patients admitted to the Critical Care Unit, 176 (14.96%) met the diagnostic criteria for sepsis. Of them, only 48 (27.3%) patients met the inclusion criteria to be enrolled in our study. The incidence of sepsis was 1.5 for every 10 admissions to the unit, with a polyneuropathy detection rate among septic patients of 0.8, based on early electrophysiological examination. The diagnostic sensitivity was 48% and specificity of 89%, with high positive predictive value (88%) and low negative predictive value (48%). Conclusion The diagnosis of polyneuropathy in critically-ill patients at an early stage is difficult and there are no useful tools cited in the literature. Early diagnosis by electrophysiology is possible in a portion of patients and is useful to establish therapeutic measures as quickly as possible and to reduce aggregate morbidity among these patients.
- Critical care medicine
- Systemic inflammatory response syndrome
ASJC Scopus subject areas
- Clinical Neurology