Urothelial susceptibility to neoplastic cellular implantation

T. E. Weldon, M. S. Soloway, L. Persky

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Although it is frequently stated that one reason for postsurgical recurrence of transitional cell carcinoma is tumor cell implantation or ''seeding,'' there have been little objective data to support this theory. In the animal model used in this study normal and inflamed urothelium were exposed to a single cell suspension of a transitional cell tumor. The data clearly show that these neoplastic cells have the ability to adhere and establish tumor growth and that mucosal damage facilitates this process. It only remains to be determined how great a role this plays in man. Recurrent tumor development as a result of implantation might be preventable, and steps should be taken to limit its occurrence.

Original languageEnglish
Pages (from-to)547-549
Number of pages3
JournalSurgical Forum
VolumeVol. 25
StatePublished - Dec 1 1974
Externally publishedYes

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Neoplasms
Urothelium
Transitional Cell Carcinoma
Suspensions
Animal Models
Recurrence
Growth

ASJC Scopus subject areas

  • Surgery

Cite this

Weldon, T. E., Soloway, M. S., & Persky, L. (1974). Urothelial susceptibility to neoplastic cellular implantation. Surgical Forum, Vol. 25, 547-549.

Urothelial susceptibility to neoplastic cellular implantation. / Weldon, T. E.; Soloway, M. S.; Persky, L.

In: Surgical Forum, Vol. Vol. 25, 01.12.1974, p. 547-549.

Research output: Contribution to journalArticle

Weldon, TE, Soloway, MS & Persky, L 1974, 'Urothelial susceptibility to neoplastic cellular implantation', Surgical Forum, vol. Vol. 25, pp. 547-549.
Weldon TE, Soloway MS, Persky L. Urothelial susceptibility to neoplastic cellular implantation. Surgical Forum. 1974 Dec 1;Vol. 25:547-549.
Weldon, T. E. ; Soloway, M. S. ; Persky, L. / Urothelial susceptibility to neoplastic cellular implantation. In: Surgical Forum. 1974 ; Vol. Vol. 25. pp. 547-549.
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