Urinary tract infections caused by Pseudomonas aeruginosa: A minireview

Rahul Mittal, Sudhir Aggarwal, Saroj Sharma, Sanjay Chhibber, Kusum Harjai

Research output: Contribution to journalReview articlepeer-review

165 Scopus citations

Abstract

Urinary tract infections (UTIs) are a serious health problem affecting millions of people each year. Infections of the urinary tract are the second most common type of infection in the body. Catheterization of the urinary tract is the most common factor, which predisposes the host to these infections. Catheter-associated UTI (CAUTI) is responsible for 40% of nosocomial infections, making it the most common cause of nosocomial infection. CAUTI accounts for more than 1 million cases in hospitals and nursing homes annually and often involve uropathogens other than Escherichia coli. While the epidemiology and pathogenic mechanisms of uropathogenic Escherichia coli have been extensively studied, little is known about the pathogenesis of UTIs caused by other organisms like Pseudomonas aeruginosa. Scanty available information regarding pathogenesis of UTIs caused by P. aeruginosa is an important bottleneck in developing effective preventive approaches. The aim of this review is to summarize some of the advances made in the field of P. aeruginosa induced UTIs and draws attention of the workers that more basic research at the level of pathogenesis is needed so that novel strategies can be designed.

Original languageEnglish (US)
Pages (from-to)101-111
Number of pages11
JournalJournal of Infection and Public Health
Volume2
Issue number3
DOIs
StatePublished - 2009
Externally publishedYes

Keywords

  • Biofilms
  • Pseudomonas aeruginosa
  • Urinary tract infections
  • Virulence factors

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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