Upper and lower tear menisci after laser in situ keratomileusis

Aizhu Tao, Meixiao Shen, Jianhua Wang, Qi Chen, Fan Lu

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objectives: To determine upper and lower tear menisci using optical coherence tomography (OCT) in volunteers after laser in situ keratomileusis (LASIK) for myopia. Methods: Thirty-five eyes of 35 nonsurgical volunteers were evaluated. Twenty-eight eyes of 28 volunteers who underwent LASIK served as the study group. The height, area, and volume of the upper and lower tear menisci were obtained in the study group, using OCT before surgery, 1 week, 1 month, and 20 months after surgery. At each visit, Schirmer test (type I, without anesthesia), tear break-up time, and corneal fluorescein staining score were evaluated. OCT imaging was conducted in the nonsurgical group with the same settings. Results: The lower tear meniscus volume at baseline were significantly smaller in the study group compared with the nonsurgical group (t test, P < 0.01). The upper tear meniscus volume decreased from 0.44 ± 0.11 μL to 0.37 ± 0.08 μL at 1 month after surgery (P < 0.05). The lower tear meniscus volume (0.54 ± 0.15 μL) reduced to 0.44 ± 0.10 μL at 1 month after surgery (posthoc, P < 0.05). For the subgroup analysis, tear menisci, Schirmer test, and tear break-up time after LASIK decreased during the first 1 month (P < 0.05) and recovered by 20 months after surgery (t test, P > 0.05). Conclusions: The upper and lower tear menisci decreased up to 1 month after LASIK and recovered by 20 months. OCT is a useful tool for evaluating the tear system in a noninvasive manner.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalEye and Contact Lens
Volume36
Issue number2
DOIs
StatePublished - Mar 1 2010

Fingerprint

Laser In Situ Keratomileusis
Tears
Optical Coherence Tomography
Volunteers
Myopia
Fluorescein
Meniscus
Anesthesia
Staining and Labeling

Keywords

  • LASIK
  • Optical coherence tomography
  • Tear meniscus

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Upper and lower tear menisci after laser in situ keratomileusis. / Tao, Aizhu; Shen, Meixiao; Wang, Jianhua; Chen, Qi; Lu, Fan.

In: Eye and Contact Lens, Vol. 36, No. 2, 01.03.2010, p. 81-85.

Research output: Contribution to journalArticle

Tao, Aizhu ; Shen, Meixiao ; Wang, Jianhua ; Chen, Qi ; Lu, Fan. / Upper and lower tear menisci after laser in situ keratomileusis. In: Eye and Contact Lens. 2010 ; Vol. 36, No. 2. pp. 81-85.
@article{d5d4c6abc75441a5be76180a6efa0dda,
title = "Upper and lower tear menisci after laser in situ keratomileusis",
abstract = "Objectives: To determine upper and lower tear menisci using optical coherence tomography (OCT) in volunteers after laser in situ keratomileusis (LASIK) for myopia. Methods: Thirty-five eyes of 35 nonsurgical volunteers were evaluated. Twenty-eight eyes of 28 volunteers who underwent LASIK served as the study group. The height, area, and volume of the upper and lower tear menisci were obtained in the study group, using OCT before surgery, 1 week, 1 month, and 20 months after surgery. At each visit, Schirmer test (type I, without anesthesia), tear break-up time, and corneal fluorescein staining score were evaluated. OCT imaging was conducted in the nonsurgical group with the same settings. Results: The lower tear meniscus volume at baseline were significantly smaller in the study group compared with the nonsurgical group (t test, P < 0.01). The upper tear meniscus volume decreased from 0.44 ± 0.11 μL to 0.37 ± 0.08 μL at 1 month after surgery (P < 0.05). The lower tear meniscus volume (0.54 ± 0.15 μL) reduced to 0.44 ± 0.10 μL at 1 month after surgery (posthoc, P < 0.05). For the subgroup analysis, tear menisci, Schirmer test, and tear break-up time after LASIK decreased during the first 1 month (P < 0.05) and recovered by 20 months after surgery (t test, P > 0.05). Conclusions: The upper and lower tear menisci decreased up to 1 month after LASIK and recovered by 20 months. OCT is a useful tool for evaluating the tear system in a noninvasive manner.",
keywords = "LASIK, Optical coherence tomography, Tear meniscus",
author = "Aizhu Tao and Meixiao Shen and Jianhua Wang and Qi Chen and Fan Lu",
year = "2010",
month = "3",
day = "1",
doi = "10.1097/ICL.0b013e3181d0b76b",
language = "English",
volume = "36",
pages = "81--85",
journal = "Eye and Contact Lense",
issn = "1542-2321",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Upper and lower tear menisci after laser in situ keratomileusis

AU - Tao, Aizhu

AU - Shen, Meixiao

AU - Wang, Jianhua

AU - Chen, Qi

AU - Lu, Fan

PY - 2010/3/1

Y1 - 2010/3/1

N2 - Objectives: To determine upper and lower tear menisci using optical coherence tomography (OCT) in volunteers after laser in situ keratomileusis (LASIK) for myopia. Methods: Thirty-five eyes of 35 nonsurgical volunteers were evaluated. Twenty-eight eyes of 28 volunteers who underwent LASIK served as the study group. The height, area, and volume of the upper and lower tear menisci were obtained in the study group, using OCT before surgery, 1 week, 1 month, and 20 months after surgery. At each visit, Schirmer test (type I, without anesthesia), tear break-up time, and corneal fluorescein staining score were evaluated. OCT imaging was conducted in the nonsurgical group with the same settings. Results: The lower tear meniscus volume at baseline were significantly smaller in the study group compared with the nonsurgical group (t test, P < 0.01). The upper tear meniscus volume decreased from 0.44 ± 0.11 μL to 0.37 ± 0.08 μL at 1 month after surgery (P < 0.05). The lower tear meniscus volume (0.54 ± 0.15 μL) reduced to 0.44 ± 0.10 μL at 1 month after surgery (posthoc, P < 0.05). For the subgroup analysis, tear menisci, Schirmer test, and tear break-up time after LASIK decreased during the first 1 month (P < 0.05) and recovered by 20 months after surgery (t test, P > 0.05). Conclusions: The upper and lower tear menisci decreased up to 1 month after LASIK and recovered by 20 months. OCT is a useful tool for evaluating the tear system in a noninvasive manner.

AB - Objectives: To determine upper and lower tear menisci using optical coherence tomography (OCT) in volunteers after laser in situ keratomileusis (LASIK) for myopia. Methods: Thirty-five eyes of 35 nonsurgical volunteers were evaluated. Twenty-eight eyes of 28 volunteers who underwent LASIK served as the study group. The height, area, and volume of the upper and lower tear menisci were obtained in the study group, using OCT before surgery, 1 week, 1 month, and 20 months after surgery. At each visit, Schirmer test (type I, without anesthesia), tear break-up time, and corneal fluorescein staining score were evaluated. OCT imaging was conducted in the nonsurgical group with the same settings. Results: The lower tear meniscus volume at baseline were significantly smaller in the study group compared with the nonsurgical group (t test, P < 0.01). The upper tear meniscus volume decreased from 0.44 ± 0.11 μL to 0.37 ± 0.08 μL at 1 month after surgery (P < 0.05). The lower tear meniscus volume (0.54 ± 0.15 μL) reduced to 0.44 ± 0.10 μL at 1 month after surgery (posthoc, P < 0.05). For the subgroup analysis, tear menisci, Schirmer test, and tear break-up time after LASIK decreased during the first 1 month (P < 0.05) and recovered by 20 months after surgery (t test, P > 0.05). Conclusions: The upper and lower tear menisci decreased up to 1 month after LASIK and recovered by 20 months. OCT is a useful tool for evaluating the tear system in a noninvasive manner.

KW - LASIK

KW - Optical coherence tomography

KW - Tear meniscus

UR - http://www.scopus.com/inward/record.url?scp=77949434157&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77949434157&partnerID=8YFLogxK

U2 - 10.1097/ICL.0b013e3181d0b76b

DO - 10.1097/ICL.0b013e3181d0b76b

M3 - Article

VL - 36

SP - 81

EP - 85

JO - Eye and Contact Lense

JF - Eye and Contact Lense

SN - 1542-2321

IS - 2

ER -