Updated osteoarthritis reference standard

W. A. Murphy, R. D. Altman

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

The Kellgren and Lawrence atlas has been the reference standard for radiographic classification of osteoarthritis (OA) for nearly 40 years. Limitations include employment of a global grade, overemphasis of the osteophyte, and submergence of other features so measurement of disease progression is difficult. Observer bias, drift, and variability cause concern. To address deficiencies and optimize observer accuracy, precision, and agreement, an updated atlas was created. From a photographic set of clinical radiographs, 4 readers selected a subset by consensus. Major radiographic features of hand, hip, and knee OA are graded on a 4-point scale. Using this atlas, it should be possible to individually score each relevant feature in a given joint. It is hoped the atlas will be adopted for population studies, assessment of disease progression, and protocols that evaluate new agents capable of modifying disease.

Original languageEnglish (US)
Pages (from-to)56-59
Number of pages4
JournalJournal of Rheumatology
Volume22
Issue numberSUPPL. 43
StatePublished - Jan 1 1995

Keywords

  • Atlas
  • Classification
  • Grading
  • Osteoarthritis
  • Radiograph

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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    Murphy, W. A., & Altman, R. D. (1995). Updated osteoarthritis reference standard. Journal of Rheumatology, 22(SUPPL. 43), 56-59.