Update on worldwide efforts to prevent type 1 diabetes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

44 Citations (Scopus)

Abstract

This paper reviews worldwide efforts to interdict the type 1 diabetes (T1D) disease process, during the stage of evolution of the disease prior to the time of disease onset. The goal of intervention before disease onset is to arrest immune destruction and thus prevent or delay clinical disease. In this regard, there have been several large-scale multicenter randomized controlled clinical trials designed to prevent T1D. These have tested nicotinamide, parenteral insulin, oral insulin, nasal insulin, and the elimination of cow's milk from infant feeding.

Original languageEnglish
Title of host publicationAnnals of the New York Academy of Sciences
Pages190-196
Number of pages7
Volume1150
DOIs
StatePublished - Dec 1 2008

Publication series

NameAnnals of the New York Academy of Sciences
Volume1150
ISSN (Print)00778923
ISSN (Electronic)17496632

Fingerprint

Medical problems
Type 1 Diabetes Mellitus
Insulin
Niacinamide
Nose
Milk
Randomized Controlled Trials

Keywords

  • Clinical trials
  • Immunomodulation
  • Prevention
  • Type 1 diabetes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Skyler, J. S. (2008). Update on worldwide efforts to prevent type 1 diabetes. In Annals of the New York Academy of Sciences (Vol. 1150, pp. 190-196). (Annals of the New York Academy of Sciences; Vol. 1150). https://doi.org/10.1196/annals.1447.055

Update on worldwide efforts to prevent type 1 diabetes. / Skyler, Jay S.

Annals of the New York Academy of Sciences. Vol. 1150 2008. p. 190-196 (Annals of the New York Academy of Sciences; Vol. 1150).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Skyler, JS 2008, Update on worldwide efforts to prevent type 1 diabetes. in Annals of the New York Academy of Sciences. vol. 1150, Annals of the New York Academy of Sciences, vol. 1150, pp. 190-196. https://doi.org/10.1196/annals.1447.055
Skyler JS. Update on worldwide efforts to prevent type 1 diabetes. In Annals of the New York Academy of Sciences. Vol. 1150. 2008. p. 190-196. (Annals of the New York Academy of Sciences). https://doi.org/10.1196/annals.1447.055
Skyler, Jay S. / Update on worldwide efforts to prevent type 1 diabetes. Annals of the New York Academy of Sciences. Vol. 1150 2008. pp. 190-196 (Annals of the New York Academy of Sciences).
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