Update on pharmacologic retinal vascular toxicity

Stephen Schwartz, Andrzej Grzybowski, Weronika Wasinska-Borowiec, Harry W Flynn, William F. Mieler

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Several medications are associated with retinal vascular toxicity. These include intraocular aminoglycosides, oral contraceptives, interferon alpha, several other agents, and talc, which occurs as a vehicle in some oral medications that may be abused intravenously. As a group, these entities represent a small but clinically relevant category of retinal toxicity from medications. Some of the manifestations (e.g., retinal vascular occlusion) are nonspecific, but others are more specific, including clinically visible talc emboli in retinal vessels. Toxicity may be asymptomatic or may cause irreversible visual loss. By maintaining a high index of suspicion, the correct diagnosis can usually be made.

Original languageEnglish (US)
Pages (from-to)4694-4697
Number of pages4
JournalCurrent Pharmaceutical Design
Volume21
Issue number32
StatePublished - Oct 1 2015

Keywords

  • Aminoglycosides
  • Interferon alpha
  • Oral contraceptives
  • Retinal vascular toxicity
  • Talc

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology

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  • Cite this

    Schwartz, S., Grzybowski, A., Wasinska-Borowiec, W., Flynn, H. W., & Mieler, W. F. (2015). Update on pharmacologic retinal vascular toxicity. Current Pharmaceutical Design, 21(32), 4694-4697.