Update on Imaging Modalities for Ocular Surface Pathologies

Osmel P. Alvarez, Anat Galor, Ghada AlBayyat, Carol L. Karp

Research output: Contribution to journalReview articlepeer-review


Purpose of Review: To discuss recent studies of imaging modalities for ocular surface pathologies. Recent Findings: Novel micro-ocular coherence tomography technology can produce high-resolution images of corneal cellular and nervous structures. Ocular coherence tomography angiography can aid in detecting early-stage limbal stem cell deficiency. Several studies used in vivo confocal microscopy to evaluate corneal nerve metrics and morphology. Summary: The applications of anterior segment optical coherence tomography, anterior segment optical coherence tomography angiography, ultrasound biomicroscopy, and in vivo confocal microscopy are useful technologies for imaging the ocular surface. Several studies have used artificial intelligence in combination with imaging technologies to create reliable and effective systems to detect and visualize ocular surface pathologies. AS OCT continues to be a key imaging tool and future development of μOCT technology may further enhance its utility.

Original languageEnglish (US)
Pages (from-to)39-47
Number of pages9
JournalCurrent Ophthalmology Reports
Issue number2
StatePublished - Jun 2021


  • Anterior segment optical coherence tomography
  • Anterior segment optical coherence tomography angiography
  • Confocal microscopy
  • Ocular surface imaging
  • Ocular surface pathologies
  • Ultrasound biomicroscopy

ASJC Scopus subject areas

  • Ophthalmology


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