Unusual Fibrillary Inclusions in Neutrophils of Human Renal Allografts

Rafael Valenzuela, Sharad D. Deodhar, William E. Braun, Lynn H.w. Banowsky

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Abstract

To the Editor: Neutrophils trapped in glomerular and paratubular capillaries of two human renal allograft biopsies showed the presence of unusual inclusions in the cytoplasm (Fig. 1, arrow) and rarely in the nuclei. The inclusions measured up to 1.6 μm by 0.1 μm, were not membrane bound, and had mostly a fibrillary substructure without any periodic banding. In addition, the neutrophils revealed degenerated mitochondria and an increase in cytoplasmic glycogen (Fig. 1, G). We are not aware of any previous report dealing with such inclusions. Linkns et al. (Linkns JA, Khoory MS, Meyers KR: Ann Intern Med 82:659, 1975). . . No extract is available for articles shorter than 400 words.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Volume295
Issue number14
DOIs
StatePublished - Sep 30 1976

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ASJC Scopus subject areas

  • Medicine(all)

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