Unusual cause of bilateral optic neuritis in a patient with AIDS

Jose G Castro, Giovanna Baldarrag

Research output: Contribution to journalArticle

Abstract

Bilateral retrobulbar optic neuritis developed in a 38-year-old woman with advanced HIV infection. This was secondary to varicella-zoster virus (VZV) infection, confirmed by polymerase chain reaction detection of VZV in the patients cerebrospinal fluid. There was no evidence of retinitis, and the ocular symptoms preceded the rash. This case illustrates that a new onset of unexplained visual loss resulting from optic neuritis in an HIV-positive patient may be caused by VZV infection. Clinicians should be aware of this unusual manifestation of VZV infection. Prompt recognition and early intervention with antivirals are needed, but it is unclear how much vision can be preserved.

Original languageEnglish
JournalAIDS Reader
StatePublished - Nov 17 2009

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Optic Neuritis
Human Herpesvirus 3
Acquired Immunodeficiency Syndrome
Virus Diseases
Retinitis
Exanthema
HIV Infections
Antiviral Agents
Cerebrospinal Fluid
HIV
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

Unusual cause of bilateral optic neuritis in a patient with AIDS. / Castro, Jose G; Baldarrag, Giovanna.

In: AIDS Reader, 17.11.2009.

Research output: Contribution to journalArticle

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