Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure

Sofía M. Muns, Mónica P. González, Victor M. Villegas, Gabriela De La Vega, Camila V. Ventura, Audina M. Berrocal

Research output: Contribution to journalArticlepeer-review


Background: To report a case of morning glory disc anomaly (MGDA) in a pediatric patient with prenatal Zika virus (ZIKV) exposure. Case presentation: A 3-year-old male with prenatal exposure to ZIKV, confirmed by real-time polymerase chain reaction testing during the second trimester of pregnancy, was evaluated due to visual loss. Physical examination was remarkable for unilateral MGDA. Neuroimaging showed a base of skull encephalocele through the floor of the sella and callosal dysgenesis. Conclusions: This is the first report to suggest an association between prenatal ZIKV exposure and MGDA. Prenatal ZIKV exposure may be associated to a wider pathologic spectrum than previously reported.

Original languageEnglish (US)
Article number36
JournalInternational Journal of Retina and Vitreous
Issue number1
StatePublished - Aug 1 2020


  • Coloboma
  • Excavated disc anomaly
  • Morning glory disc anomaly
  • Optic disc
  • Zika virus

ASJC Scopus subject areas

  • Ophthalmology


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